Protein function
Encodes a subunit of the PRC2 complex, which is involed in histone methylation.
Phenotype
Function:Polycomb group (PcG) protein. Catalytic subunit of some PcG multiprotein complex, which methylates Lys-27 of histone H3, leading to transcriptional repression of the affected target genes. Required to prevent the proliferation of the central cell of the female gametophyte by repressing target genes before fertilization. After fertilization, it probably also regulates the embryo and endosperm proliferation and anteroposterior organization during seed development. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. Interacts with the promoter and repress the transcription of genes such as PHE1 and PHE2, that are paternally active and maternally silenced genes.
[Data from UniProt]
Regulators, targets and interactors
Downstream actors
Upstream actors
Protein-protein interactions
FIE1, FIS3 --
[Spillane et al., 2000][Yadegari et al., 2000] --
[View TAIR record]