Detailed gene information

Genes [306]




MRG2
MORF RELATED GENE2
TAIR: AT1G02740
UNIPROT: Q4V3E2
NOWOMICS: View List

Publications

Bu Z et al., 2014, PLoS Genet.
Xu Y et al., 2014, Nucleic Acids Res.

Appears in the following schemes

Time-course regulation of photoperiodic pathway
General processes & autonomous pathway

Protein function

Encodes a chromatin-binding protein.

Phenotype

Multiple mutant:
mrg1;mrg2 multiple mutant is late flowering under LD conditions only. [Bu et al., 2014]

Single mutant:
mrg2 single mutant does not display any flowering-time phenotype. [Bu et al., 2014]

Remarks:
MRG2 binds to the FT promoter in a H3K4me3/H3K36me3- and CO-dependent manner. [Bu et al., 2014]

Function:
Chromatin remodeling factor. Acts as a reader protein by binding to H3K4me3 and H3K36me3 to control histone H4 acetylation. Increases the transcriptional levels of the flowering time genes FLC and FT (PubMed:25183522, PubMed:25211338). Binds the chromatin at the FT promoter upon interaction with CO (PubMed:25211338). [Data from UniProt]

Regulators, targets and interactors

Downstream actors

causality
FT -- [Xu et al., 2014][Bu et al., 2014] -- [View TAIR record]



Upstream actors


Protein-protein interactions

CO -- [Bu et al., 2014] -- [View TAIR record]



MRG2 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins