Detailed gene information

Genes [306]




GI
GIGANTEA
TAIR: AT1G22770
UNIPROT: Q9SQI2
NOWOMICS: View List

Publications

Koornneef M et al., 1991, Mol. Gen. Genet.
Kurepa J et al., 1998, Plant J.
Fowler S et al., 1999, EMBO J.
Park D H et al., 1999, Science
Huq E et al., 2000, Proc. Natl. Acad. Sci. U.S.A.
Mizoguchi T et al., 2005, Plant Cell
Sawa M et al., 2007, Science
Kim W et al., 2007, Nature
Sawa M et al., 2011, Proc. Natl. Acad. Sci. U.S.A.

Appears in the following schemes

Overview
Aging pathway
Circadian clock overview
Photoperiod pathway
Time-course regulation of photoperiodic pathway
Sugar pathway

Protein function

Encodes a component of the circadian clock.

Phenotype

Overexpressor:
GI overexpressor is early flowering under both SD and LD conditions. ( The flowering-time phenotype is much stronger under SD conditions.) [Fornara et al., 2009][Mizoguchi et al., 2005][Sawa et al., 2011]

Single mutant:
gi single mutant is late flowering under LD conditions only. ( Some gi mutant lines seems to be slightly late flowering under SD conditions as well.) [Fornara et al., 2009][Sawa et al., 2007][Fowler et al., 1999][Mizoguchi et al., 2005][Sawa et al., 2011]

Function:
Involved in regulation of circadian rhythm and photoperiodic flowering. May play a role in maintenance of circadian amplitude and period length. Is involved in phytochrome B signaling. Stabilizes ADO3 and the circadian photoreceptor ADO1/ZTL. Regulates CONSTANS (CO) in the long-day flowering pathway by modulating the ADO3-dependent protein stability of CDF1 and CDF2, but is not essential to activate CO transcription. Regulates, via the microRNA miR172, a CO-independent pathway that promotes photoperiodic flowering by inducing FLOWERING LOCUS T . [Data from UniProt]

Regulators, targets and interactors

Downstream actors

causality
FT -- [Sawa et al., 2011][Mizoguchi et al., 2005] -- [View TAIR record]

CDF3 -- [Fornara et al., 2009][Kim et al., 2007][Imaizumi et al., 2005][Sawa et al., 2007] -- [View TAIR record]

CO -- [Fornara et al., 2009][Song et al., 2014][Mizoguchi et al., 2005][Imaizumi et al., 2005][Sawa et al., 2007][Song et al., 2012] -- [View TAIR record]

MIR172C -- [Jung et al., 2007] -- [View TAIR record]

CDF2 -- [Fornara et al., 2009][Kim et al., 2007][Imaizumi et al., 2005][Sawa et al., 2007] -- [View TAIR record]

CDF5 -- [Fornara et al., 2009][Kim et al., 2007][Imaizumi et al., 2005][Sawa et al., 2007] -- [View TAIR record]

MIR172B -- [Jung et al., 2007] -- [View TAIR record]

CDF1 -- [Fornara et al., 2009][Kim et al., 2007][Imaizumi et al., 2005][Sawa et al., 2007] -- [View TAIR record]

CDF4 -- [Fornara et al., 2009][Kim et al., 2007][Imaizumi et al., 2005][Sawa et al., 2007] -- [View TAIR record]

MIR172A -- [Jung et al., 2007] -- [View TAIR record]

ZTL -- [Fornara et al., 2009][Kim et al., 2007][Kim et al., 2013] -- [View TAIR record]



Upstream actors

causality
ELF3 -- [Helfer et al., 2011][Yu et al., 2008][Kolmos et al., 2007] -- [View TAIR record]

LATE -- [Weingartner et al., 2011] -- [View TAIR record]

TOC1 -- [Huang et al., 2012] -- [View TAIR record]

ELF4 -- [Kim et al., 2013][Helfer et al., 2011][Kolmos et al., 2007] -- [View TAIR record]

LUX, PCL1 -- [Helfer et al., 2011][Kolmos et al., 2007] -- [View TAIR record]

DET1, FUS2 -- [Kang et al., 2015] -- [View TAIR record]

COP1 -- [Yu et al., 2008] -- [View TAIR record]

BOA -- [Helfer et al., 2011][Kolmos et al., 2007] -- [View TAIR record]

CCA1 -- [Lu et al., 2012] -- [View TAIR record]



Protein-protein interactions

TEM1, EDF1 -- [Sawa et al., 2011] -- [View TAIR record]

FKF1, ADO3 -- [Fornara et al., 2009][Song et al., 2014][Sawa et al., 2007] -- [View TAIR record]

TEM2, RAV2 -- [Sawa et al., 2011] -- [View TAIR record]

CDF5 -- [Fornara et al., 2009][Kim et al., 2007][Imaizumi et al., 2005][Sawa et al., 2007] -- [View TAIR record]

LKP2 -- [Fornara et al., 2009][Kim et al., 2007] -- [View TAIR record]

SVP -- [Sawa et al., 2011] -- [View TAIR record]

CDF4 -- [Fornara et al., 2009][Kim et al., 2007][Imaizumi et al., 2005][Sawa et al., 2007] -- [View TAIR record]

CDF3 -- [Fornara et al., 2009][Kim et al., 2007][Imaizumi et al., 2005][Sawa et al., 2007] -- [View TAIR record]

CDF2 -- [Fornara et al., 2009][Kim et al., 2007][Imaizumi et al., 2005][Sawa et al., 2007] -- [View TAIR record]

ZTL -- [Fornara et al., 2009][Kim et al., 2007][Kim et al., 2013] -- [View TAIR record]

CDF1 -- [Fornara et al., 2009][Kim et al., 2007][Imaizumi et al., 2005][Sawa et al., 2007] -- [View TAIR record]


ELF4 -- [Kim et al., 2013][Helfer et al., 2011][Kolmos et al., 2007] -- [View TAIR record]

DET1, FUS2 -- [Kang et al., 2015] -- [View TAIR record]

CO -- [Song et al., 2014] -- [View TAIR record]

ZTL -- [Kim et al., 2007] -- [View TAIR record]



GI interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins