Detailed gene information

Genes [306]

DCL1LHYGA2ox6MRG2CRY2ATPRMT10ATX2STOESD7, TIL1, ABO4NF-YC9, HAP5CPHYACIB4OTS2LWD1, ATAN11UBC1GAI, RGA2GA3OX1TPLCSTF77ARP4AFR2GIPFT1, MED25TEM1, EDF1CIB5CUL3AVOZ1GA2ox2SUF4FRL2RCD1FBH1GA2ox4CPK33GA2ox7FBH3, AKS1, BHLH122ASH2R, TROHTA9SPA4SPL4RRP6L1NF-YC3HUB2MED13, GCT, MAB2VIM1, ORTH2OTS1, ULP1DVIP5LDL1FTVIM2RGL1AT-STUbl4FKF1, ADO3TEM2, RAV2AP1CDF5CSTF64PHLAFR1SDG26, ASHH1FLM, MAF1, AGL27EFS, SDG8GA2ox1TPS1APL, WDY, FEGA2, ATKS1ELF7PRP8, SUS2, EMB33GA3OX2RGA1UBC2EFMELF8, VIP6ABH1, CBP80CPK6FDP, BZIP27PHYBVIL3, VEL2LKP2MIR156GFVE, MSI4GLK1, GPRI1FIO1GRP7, CCR2MED18SVPAGL17CLF, SDG1SUVR5MIR156AELF3ATCMIR172ATOE1, RAP2.7PUB12FLXUGT87A2ATX1, SDG27COP1SPL3FES1CDF4GA2ox3NF-YA4JMJ15, MEE27SRO1AS1HTA8NF-YB1, HAP3ASNZESD6, HOS1ELF4SPL9FBH4, AKS3VOZ2PIF4FPASDG7, ASSH3CKB4HUB1AHL22AGL6SOC1, AGL20BRM, CHR2LRB1SPA1PRR9CCA1RFI2HULK2AKIN10, SNRK1.1MBD9GASA5RGL2MYR2FLKGID1ACOL9FLD, RSI1MIR172CUBP13PIE1LDL2SPL5SPA3BRC1, TCP18VRN1DNFFIE1, FIS3JMJ30TICPHP, CDC73AtBMI1CVIL1, VRN5LWD2ICE1, SCRMSSRP1, HMG, NFDMYB30ARP6, SUF3, ESD1SUS4DCL3ATJ3HDA9JMJ32, JMJD5PUB13LUX, PCL1CDF3REF6, JMJ12UBP26WDR5ALNK2HTA11SMZAGL16INO80AGL18SPL15PIF5, PIL6CKB3LRB2, POB1GID1BHULK3MED12, CCT, CRPFRILIF2LDGA1AtNDXMED16, SFR6CRY1FBH2DET1, FUS2SPT16XAL2, AGL14NF-YB3, HAP3CESD4PHYDFCAVRN2PHYETSFJMJ14, PKDM7B, JMJ4GA2ox8EBSAGL19CAD2, RML1, GSH1AGL24PGI1MOS1GA20ox1FWA, HDG6WRKY34, MSP3ULT1HXK1, GIN2VIP3, SKI8VIL2, VEL1MIR156BSKB1, PRMT5MIR156CATH1CIB1FDAP2MRG1CSP2, GRP2BBX19SHL1, SHLHB16, ATHB16PRR7TFL1ELF6MIR172BSUC9UBP12FTIP1GA20OX3HAM2, HAG5, HAC11FLC, AGL25, FLFMIR156DEMF1MIR156ENF-YA1, HAP2BFYAGL15BAF60, CHC1COFRL1, SUF8RGL3TFL2, LHP1MYR1DCL4HUA2RUP2, EFO2PRR5FPF1MIR156FGID1CPHYCRRP6L2SEF, SWC6RVE2, CIR1VIM3, ORTH1CDF2HLP1ATXR7, SDG25IDD8, NUCGLK2CBP20YAF9A, TAF14B, GAS41CUL4NF-YB2, HAP3BADG1, APS1CIB2LATEPRMT4AEMF2, CYR1GA20ox2PGM1MIR156HZTLVIN3COL5MSI1SRR1PRR3TOE2SIZ1FUL, AGL8HDA5VIP4TOC1LFYFLX4, FLL4BFTCDF1HDA6, RTS1NF-YC4GIS5, EMB2780LNK1HAM1CDKC;2MAF2, AGL31MAF3, AGL70MAF4, AGL69MAF5, AGL68TOE3

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Publications

Ma H et al., 1991, Genes Dev.
Pelaz S et al., 2000, Nature
Pelaz S et al., 2001, Curr. Biol.
Honma T et al., 2001, Nature
Favaro R et al., 2003, Plant Cell
Zahn L M et al., 2005, Genetics
Castillejo C et al., 2005, Plant J.
Kaufmann K et al., 2009, PLoS Biol.
Jetha K et al., 2014, Nucleic Acids Res.
Puranik S et al., 2014, Plant Cell

Appears in the following schemes

Flower development
Mains targets of ABC(E)genes
Kinetics of ABC(E) genes expression
Specification of flower meristems
Vernalization

Protein function

Encodes a MADS-box transcription factor.

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Phenotype

Multiple mutant:
sep1;sep2;sep3 multiple mutant produces flowers in which all organs develop as sepals. [Pelaz et al., 2000]

Overexpressor:
SEP3 overexpression promotes the transformation of sepals and inflorescence meristems into carpeloid structures. [Castillejo et al., 2005]

Function:
Probable transcription factor active in inflorescence development and floral organogenesis. Functions with SEPALLATA1/AGL2 and SEPALLATA2/AGL4 to ensure proper development of petals, stamens and carpels and to prevent the indeterminate growth of the flower meristem. Interacts with APETALA1, AGAMOUS or APETALA3/PISTILLATA to form complexes, that could be involved in genes regulation during floral meristem development. [Data from UniProt]

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Regulators, targets and interactors

Downstream actors

causality
PI -- [Wu et al., 2012][Wuest et al., 2012][ÓMaoiléidigh et al., 2013][Kaufmann et al., 2010][Sridhar et al., 2006][Kaufmann et al., 2009] -- [View TAIR record]

SHP1, AGL1 -- [Kaufmann et al., 2009] -- [View TAIR record]

AP1 -- [Wuest et al., 2012][Kaufmann et al., 2009][Gustafson-Brown et al., 1994] -- [View TAIR record]

FD -- [Wuest et al., 2012][Gregis et al., 2008][Kaufmann et al., 2010][Liu et al., 2007] -- [View TAIR record]

TOE1, RAP2.7 -- [Wuest et al., 2012][Gregis et al., 2008][Kaufmann et al., 2010][Liu et al., 2007] -- [View TAIR record]

PTL -- [Wuest et al., 2012] -- [View TAIR record]

UFO -- [Wuest et al., 2012][ÓMaoiléidigh et al., 2013] -- [View TAIR record]

AG -- [Wuest et al., 2012][Conner et al., 2000][ÓMaoiléidigh et al., 2013][Ó Maoiléidigh et al., 2014][Sridhar et al., 2006][Kaufmann et al., 2009][Franks et al., 2002] -- [View TAIR record]

AGL24 -- [Wuest et al., 2012][Gregis et al., 2008][Kaufmann et al., 2010][Liu et al., 2007] -- [View TAIR record]

SVP -- [Wuest et al., 2012][Gregis et al., 2008][Kaufmann et al., 2010][Liu et al., 2007] -- [View TAIR record]

INO -- [Wuest et al., 2012][ÓMaoiléidigh et al., 2013] -- [View TAIR record]

SPL, NZZ -- [Wuest et al., 2012][ÓMaoiléidigh et al., 2013] -- [View TAIR record]

AP3 -- [Wu et al., 2012][Wuest et al., 2012][ÓMaoiléidigh et al., 2013][Kaufmann et al., 2010][Sridhar et al., 2006][Kaufmann et al., 2009] -- [View TAIR record]

SEP3 -- [Wuest et al., 2012][ÓMaoiléidigh et al., 2013][Kaufmann et al., 2009] -- [View TAIR record]

SOC1, AGL20 -- [Wuest et al., 2012][Gregis et al., 2008][Kaufmann et al., 2010][Liu et al., 2007] -- [View TAIR record]

SHP2, AGL5 -- [Wuest et al., 2012][ÓMaoiléidigh et al., 2013] -- [View TAIR record]

SUP, FLO10 -- [Wuest et al., 2012][ÓMaoiléidigh et al., 2013] -- [View TAIR record]

Upstream actors

causality
CLF, SDG1 -- [Jiang et al., 2008][Lopez-Vernaza et al., 2012] -- [View TAIR record]

BAF60, CHC1 -- [Sacharowski et al., 2015] -- [View TAIR record]

TFL2, LHP1 -- [Liu et al., 2009] -- [View TAIR record]

SVP -- [Liu et al., 2009][Liu et al., 2013][Posé et al., 2013] -- [View TAIR record]

PNY, RPL, BLR -- [Smaczniak et al., 2012] -- [View TAIR record]

PI -- [Honma et al., 2001][Smaczniak et al., 2012][Wuest et al., 2012][ÓMaoiléidigh et al., 2013] -- [View TAIR record]

FLC, AGL25, FLF -- [Deng et al., 2011][Mateos et al., 2015] -- [View TAIR record]

AGL24 -- [Liu et al., 2009][Liu et al., 2013] -- [View TAIR record]

FLM, MAF1, AGL27 -- [Posé et al., 2013] -- [View TAIR record]

TPL -- [Krogan et al., 2012] -- [View TAIR record]

SEP3 -- [Wuest et al., 2012][ÓMaoiléidigh et al., 2013][Kaufmann et al., 2009] -- [View TAIR record]

AG -- [Wuest et al., 2012][Favaro et al., 2003][ÓMaoiléidigh et al., 2013][Kaufmann et al., 2009] -- [View TAIR record]

SOC1, AGL20 -- [Liu et al., 2009][Liu et al., 2013][Immink et al., 2012] -- [View TAIR record]

AP2 -- [Yant et al., 2010][Krogan et al., 2012] -- [View TAIR record]

HDA1, HDA19, -- [Krogan et al., 2012] -- [View TAIR record]

AP1 -- [Honma et al., 2001][Smaczniak et al., 2012][Wuest et al., 2012][Liu et al., 2007][Kaufmann et al., 2009][Pelaz et al., 2001] -- [View TAIR record]

AP3 -- [Wuest et al., 2012][ÓMaoiléidigh et al., 2013] -- [View TAIR record]

Protein-protein interactions

SEU -- [Conner et al., 2000][Sridhar et al., 2006][Franks et al., 2002] -- [View TAIR record]

LUG -- [Conner et al., 2000][Sridhar et al., 2006][Franks et al., 2002] -- [View TAIR record]


SEU -- [Sridhar et al., 2006] -- [View TAIR record]

AP1 -- [Honma et al., 2001][Smaczniak et al., 2012][Wuest et al., 2012][Liu et al., 2007][Kaufmann et al., 2009][Pelaz et al., 2001] -- [View TAIR record]

SHP2, AGL5 -- [Favaro et al., 2003] -- [View TAIR record]

SHP1, AGL1 -- [Favaro et al., 2003] -- [View TAIR record]

STK, AGL11 -- [Favaro et al., 2003] -- [View TAIR record]

AG -- [Wuest et al., 2012][Favaro et al., 2003][ÓMaoiléidigh et al., 2013][Kaufmann et al., 2009] -- [View TAIR record]

LUG -- [Sridhar et al., 2006] -- [View TAIR record]

PNY, RPL, BLR -- [Smaczniak et al., 2012] -- [View TAIR record]

PI -- [Honma et al., 2001][Smaczniak et al., 2012][Wuest et al., 2012][ÓMaoiléidigh et al., 2013] -- [View TAIR record]

LFY -- [Liu et al., 2009] -- [View TAIR record]

SEP3 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins