Detailed gene information

Genes [306]

DCL1LHYGA2ox6MRG2CRY2ATPRMT10ATX2STOESD7, TIL1, ABO4NF-YC9, HAP5CPHYACIB4OTS2LWD1, ATAN11UBC1GAI, RGA2GA3OX1TPLCSTF77ARP4AFR2GIPFT1, MED25TEM1, EDF1CIB5CUL3AVOZ1GA2ox2SUF4FRL2RCD1FBH1GA2ox4CPK33GA2ox7FBH3, AKS1, BHLH122ASH2R, TROHTA9SPA4SPL4RRP6L1NF-YC3HUB2MED13, GCT, MAB2VIM1, ORTH2OTS1, ULP1DVIP5LDL1FTVIM2RGL1AT-STUbl4FKF1, ADO3TEM2, RAV2AP1CDF5CSTF64PHLAFR1SDG26, ASHH1FLM, MAF1, AGL27EFS, SDG8GA2ox1TPS1APL, WDY, FEGA2, ATKS1ELF7PRP8, SUS2, EMB33GA3OX2RGA1UBC2EFMELF8, VIP6ABH1, CBP80CPK6FDP, BZIP27PHYBVIL3, VEL2LKP2MIR156GFVE, MSI4GLK1, GPRI1FIO1GRP7, CCR2MED18SVPAGL17CLF, SDG1SUVR5MIR156AELF3ATCMIR172ATOE1, RAP2.7PUB12FLXUGT87A2ATX1, SDG27COP1SPL3FES1CDF4GA2ox3NF-YA4JMJ15, MEE27SRO1AS1HTA8NF-YB1, HAP3ASNZESD6, HOS1ELF4SPL9FBH4, AKS3VOZ2PIF4FPASDG7, ASSH3CKB4HUB1AHL22AGL6SOC1, AGL20BRM, CHR2LRB1SPA1PRR9CCA1RFI2HULK2AKIN10, SNRK1.1MBD9GASA5RGL2MYR2FLKGID1ACOL9FLD, RSI1MIR172CUBP13PIE1LDL2SPL5SPA3BRC1, TCP18VRN1DNFFIE1, FIS3JMJ30TICPHP, CDC73AtBMI1CVIL1, VRN5LWD2ICE1, SCRMSSRP1, HMG, NFDMYB30ARP6, SUF3, ESD1SUS4DCL3ATJ3HDA9JMJ32, JMJD5PUB13LUX, PCL1CDF3REF6, JMJ12UBP26WDR5ALNK2HTA11SMZAGL16INO80AGL18SPL15PIF5, PIL6CKB3LRB2, POB1GID1BHULK3MED12, CCT, CRPFRILIF2LDGA1AtNDXMED16, SFR6CRY1FBH2DET1, FUS2SPT16XAL2, AGL14NF-YB3, HAP3CESD4PHYDFCAVRN2PHYETSFJMJ14, PKDM7B, JMJ4GA2ox8EBSAGL19CAD2, RML1, GSH1AGL24PGI1MOS1GA20ox1FWA, HDG6WRKY34, MSP3ULT1HXK1, GIN2VIP3, SKI8VIL2, VEL1MIR156BSKB1, PRMT5MIR156CATH1CIB1FDAP2MRG1CSP2, GRP2BBX19SHL1, SHLHB16, ATHB16PRR7TFL1ELF6MIR172BSUC9UBP12FTIP1GA20OX3HAM2, HAG5, HAC11FLC, AGL25, FLFMIR156DEMF1MIR156ENF-YA1, HAP2BFYAGL15BAF60, CHC1COFRL1, SUF8RGL3TFL2, LHP1MYR1DCL4HUA2RUP2, EFO2PRR5FPF1MIR156FGID1CPHYCRRP6L2SEF, SWC6RVE2, CIR1VIM3, ORTH1CDF2HLP1ATXR7, SDG25IDD8, NUCGLK2CBP20YAF9A, TAF14B, GAS41CUL4NF-YB2, HAP3BADG1, APS1CIB2LATEPRMT4AEMF2, CYR1GA20ox2PGM1MIR156HZTLVIN3COL5MSI1SRR1PRR3TOE2SIZ1FUL, AGL8HDA5VIP4TOC1LFYFLX4, FLL4BFTCDF1HDA6, RTS1NF-YC4GIS5, EMB2780LNK1HAM1CDKC;2MAF2, AGL31MAF3, AGL70MAF4, AGL69MAF5, AGL68TOE3

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Publications

Koornneef M et al., 1982, Mutat. Res.
Irish V F et al., 1990, Plant Cell
Mandel M A et al., 1992, Nature
Gustafson-Brown C et al., 1994, Cell
Mandel M A et al., 1995, Nature
Mandel M A et al., 1995, Plant Cell
Simon R et al., 1996, Nature
Cho S et al., 1999, Plant Mol. Biol.
Peña L et al., 2001, Nat. Biotechnol.
Gregis V et al., 2009, Plant J.
Han Y et al., 2014, Proc. Natl. Acad. Sci. U.S.A.

Appears in the following schemes

Overview
Temperature pathway
Aging pathway
Photoperiod pathway
Sugar pathway
Flower development
Mains targets of ABC(E)genes
Kinetics of ABC(E) genes expression
Specification of flower meristems
Vernalization

Protein function

Encodes a MADS-box transcription factor.

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Phenotype

Overexpressor:
AP1 overexpressor is early flowering and shows transformation of apical and lateral shoots into flowers. [Mandel et al., 1995]

Single mutant:
ap1 single mutant shows abnormal flower development: sepals are converted into bracts. [Irish et al., 1990]

Function:
Transcription factor that promotes early floral meristem identity in synergy with LEAFY. Is required subsequently for the transition of an inflorescence meristem into a floral meristem. Is indispensable for normal development of sepals and petals in flowers. Regulates positively the B class homeotic proteins APETALA3 and PISTILLATA with the cooperation of LEAFY and UFO. Interacts with SEPALLATA3 or AP3/PI heterodimer to form complexes that could be involved in genes regulation during floral meristem development. Regulates positively AGAMOUS in cooperation with LEAFY. Displays a redundant function with CAULIFLOWER in the up-regulation of LEAFY. Together with AGL24 and SVP, controls the identity of the floral meristem and regulates expression of class B, C and E genes. Represses flowering time genes AGL24, SVP and SOC1 in emerging floral meristems. [Data from UniProt]

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Regulators, targets and interactors

Downstream actors

causality
AGL24 -- [Yu et al., 2004][Wuest et al., 2012][Gregis et al., 2008][Kaufmann et al., 2010][Liu et al., 2007] -- [View TAIR record]

SHP2, AGL5 -- [Wuest et al., 2012] -- [View TAIR record]

TFL1 -- [Kaufmann et al., 2010] -- [View TAIR record]

SUP, FLO10 -- [Wuest et al., 2012] -- [View TAIR record]

TEM1, EDF1 -- [Kaufmann et al., 2010] -- [View TAIR record]

FDP, BZIP27 -- [Kaufmann et al., 2010] -- [View TAIR record]

AP3 -- [Honma et al., 2001][Smaczniak et al., 2012][Wu et al., 2012][Wuest et al., 2012][Kaufmann et al., 2010][Weigel et al., 1993][Liu et al., 2007][Sridhar et al., 2006][Kaufmann et al., 2009][Lamb et al., 2002] -- [View TAIR record]

SOC1, AGL20 -- [Wuest et al., 2012][Gregis et al., 2008][Kaufmann et al., 2010][Liu et al., 2007] -- [View TAIR record]

FD -- [Wuest et al., 2012][Gregis et al., 2008][Kaufmann et al., 2010][Liu et al., 2007] -- [View TAIR record]

LFY -- [Smaczniak et al., 2012][Kaufmann et al., 2010][Wellmer et al., 2006] -- [View TAIR record]

PTL -- [Wuest et al., 2012] -- [View TAIR record]

TOE3 -- [Kaufmann et al., 2010] -- [View TAIR record]

UFO -- [Wuest et al., 2012] -- [View TAIR record]

PI -- [Honma et al., 2001][Smaczniak et al., 2012][Wu et al., 2012][Wuest et al., 2012][Kaufmann et al., 2010][Weigel et al., 1993][Liu et al., 2007][Sridhar et al., 2006][Kaufmann et al., 2009][Lamb et al., 2002] -- [View TAIR record]

AP2 -- [Smaczniak et al., 2012] -- [View TAIR record]

SEP3 -- [Honma et al., 2001][Smaczniak et al., 2012][Wuest et al., 2012][Liu et al., 2007][Kaufmann et al., 2009][Pelaz et al., 2001] -- [View TAIR record]

SVP -- [Yu et al., 2004][Wuest et al., 2012][Gregis et al., 2008][Kaufmann et al., 2010][Liu et al., 2007] -- [View TAIR record]

INO -- [Wuest et al., 2012] -- [View TAIR record]

TOE1, RAP2.7 -- [Smaczniak et al., 2012][Wuest et al., 2012][Gregis et al., 2008][Kaufmann et al., 2010][Liu et al., 2007] -- [View TAIR record]

SPL, NZZ -- [Wuest et al., 2012] -- [View TAIR record]

TEM2, RAV2 -- [Kaufmann et al., 2010] -- [View TAIR record]

AG -- [Conner et al., 2000][Bao et al., 2004][Sridhar et al., 2006][Franks et al., 2002] -- [View TAIR record]

AP1 -- [Wuest et al., 2012][Kaufmann et al., 2009] -- [View TAIR record]

Upstream actors

causality
FT -- [Teper-Bamnolker et al., 2005][Wigge et al., 2005][Abe et al., 2005] -- [View TAIR record]

SVP -- [Grandi et al., 2012] -- [View TAIR record]

SPL4 -- [Wang et al., 2009][Yamaguchi et al., 2009] -- [View TAIR record]

PI -- [Wuest et al., 2012] -- [View TAIR record]

AP2 -- [Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]

BAF60, CHC1 -- [Sacharowski et al., 2015] -- [View TAIR record]

SMZ -- [Mathieu et al., 2009] -- [View TAIR record]

LMI2, MYB17 -- [Pastore et al., 2011] -- [View TAIR record]

AGL24 -- [Grandi et al., 2012] -- [View TAIR record]

SPL3 -- [Wang et al., 2009][Yamaguchi et al., 2009] -- [View TAIR record]

SEP3 -- [Wuest et al., 2012][Kaufmann et al., 2009][Gustafson-Brown et al., 1994] -- [View TAIR record]

AGL17 -- [Han et al., 2008] -- [View TAIR record]

AG -- [Kaufmann et al., 2009][Gustafson-Brown et al., 1994] -- [View TAIR record]

SPL9 -- [Wang et al., 2009][Yamaguchi et al., 2014] -- [View TAIR record]

TFL1 -- [Ratcliffe et al., 1999] -- [View TAIR record]

CAL -- -- [View TAIR record]

FD -- [Teper-Bamnolker et al., 2005][Wigge et al., 2005][Abe et al., 2005] -- [View TAIR record]

AP1 -- [Wuest et al., 2012][Kaufmann et al., 2009] -- [View TAIR record]

SPL5 -- [Wang et al., 2009][Yamaguchi et al., 2009] -- [View TAIR record]

AP3 -- [Wuest et al., 2012] -- [View TAIR record]

RGA1 -- [Yamaguchi et al., 2014] -- [View TAIR record]

LFY -- [Liu et al., 2009][Winter et al., 2011][Grandi et al., 2012][Wagner et al., 1999] -- [View TAIR record]

PNY, RPL, BLR -- [Smaczniak et al., 2012] -- [View TAIR record]

Protein-protein interactions

SEP3 -- [Honma et al., 2001][Smaczniak et al., 2012][Wuest et al., 2012][Liu et al., 2007][Kaufmann et al., 2009][Pelaz et al., 2001] -- [View TAIR record]

SEU -- [Conner et al., 2000][Sridhar et al., 2006][Smaczniak et al., 2012][Franks et al., 2002] -- [View TAIR record]

AP3 -- [Honma et al., 2001][Smaczniak et al., 2012][Wu et al., 2012][Wuest et al., 2012][Kaufmann et al., 2010][Weigel et al., 1993][Liu et al., 2007][Sridhar et al., 2006][Kaufmann et al., 2009][Lamb et al., 2002] -- [View TAIR record]

LUG -- [Conner et al., 2000][Sridhar et al., 2006][Smaczniak et al., 2012][Franks et al., 2002] -- [View TAIR record]

PI -- [Honma et al., 2001][Smaczniak et al., 2012][Wu et al., 2012][Wuest et al., 2012][Kaufmann et al., 2010][Weigel et al., 1993][Liu et al., 2007][Sridhar et al., 2006][Kaufmann et al., 2009][Lamb et al., 2002] -- [View TAIR record]


SEU -- [Sridhar et al., 2006] -- [View TAIR record]

LUG -- [Sridhar et al., 2006] -- [View TAIR record]

PNY, RPL, BLR -- [Smaczniak et al., 2012] -- [View TAIR record]

AP1 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins