Protein function
Encodes a RNA binding protein that mediates the 3-end processing of mRNA.
Phenotype
Remarks: CSTF64 is involved in the 3 -end processing of the antisense
FLC mRNA.
cstf64 single mutant has increased
FLC expression levels.
[Liu et al., 2010] Function:One of the multiple factors required for polyadenylation and 3 -end cleavage of pre-mRNAs (By similarity). This subunit is directly involved in the binding to pre-mRNAs, especially on the 3 non-coding region (PubMed:12379796). Required for the targeted 3 processing of antisense transcripts that triggers transcriptional silencing of the corresponding sense gene (PubMed:17008405, PubMed:19965720).
[Data from UniProt]
Regulators, targets and interactors
Downstream actors
causality FLC, AGL25, FLF --
[Liu et al., 2010] --
[View TAIR record] Upstream actors
Protein-protein interactions