Detailed gene information

Genes [306]




SDG26, ASHH1
SET DOMAIN GROUP 26, ASH1-RELATED PROTEIN 1
TAIR: AT1G76710
UNIPROT: Q84WW6
NOWOMICS: View List

Publications

Masucci M T et al., 1989, Tumori
Xu L et al., 2008, Mol. Cell. Biol.
Valencia-Morales M d P et al., 2012, J. Plant Res.
Berr A et al., 2015, Plant J.

Appears in the following schemes

General processes & autonomous pathway

Protein function

Encodes a histone methylantransferase.

Phenotype

Single mutant:
sdg26 single mutant is late flowering under both SD and LD conditions. [Xu et al., 2008][Berr et al., 2015]

Remarks:
The late-flowering phenotype of the sdg26 single mutant is caused by increased FLC and MAF expression levels. The mechanisms through which this upregulation occurs remains unclear. SDG26 also binds to the SOC1 locus. [Xu et al., 2008][Berr et al., 2015]

Function:
Histone methyltransferase involved in regulation of flowering time. Required for the expression of the SOC1/AGL20 gene. Required for histone H3 trimethylation on Lys-4 H3K4me3 at the SOC1 locus. Prevents trimethylation on Lys-27 H3K276me3 at the same locus. [Data from UniProt]

Regulators, targets and interactors

Downstream actors


Upstream actors


Protein-protein interactions


SDG26, ASHH1 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins