Detailed gene information

Genes [306]

DCL1LHYGA2ox6MRG2CRY2ATPRMT10ATX2STOESD7, TIL1, ABO4NF-YC9, HAP5CPHYACIB4OTS2LWD1, ATAN11UBC1GAI, RGA2GA3OX1TPLCSTF77ARP4AFR2GIPFT1, MED25TEM1, EDF1CIB5CUL3AVOZ1GA2ox2SUF4FRL2RCD1FBH1GA2ox4CPK33GA2ox7FBH3, AKS1, BHLH122ASH2R, TROHTA9SPA4SPL4RRP6L1NF-YC3HUB2MED13, GCT, MAB2VIM1, ORTH2OTS1, ULP1DVIP5LDL1FTVIM2RGL1AT-STUbl4FKF1, ADO3TEM2, RAV2AP1CDF5CSTF64PHLAFR1SDG26, ASHH1FLM, MAF1, AGL27EFS, SDG8GA2ox1TPS1APL, WDY, FEGA2, ATKS1ELF7PRP8, SUS2, EMB33GA3OX2RGA1UBC2EFMELF8, VIP6ABH1, CBP80CPK6FDP, BZIP27PHYBVIL3, VEL2LKP2MIR156GFVE, MSI4GLK1, GPRI1FIO1GRP7, CCR2MED18SVPAGL17CLF, SDG1SUVR5MIR156AELF3ATCMIR172ATOE1, RAP2.7PUB12FLXUGT87A2ATX1, SDG27COP1SPL3FES1CDF4GA2ox3NF-YA4JMJ15, MEE27SRO1AS1HTA8NF-YB1, HAP3ASNZESD6, HOS1ELF4SPL9FBH4, AKS3VOZ2PIF4FPASDG7, ASSH3CKB4HUB1AHL22AGL6SOC1, AGL20BRM, CHR2LRB1SPA1PRR9CCA1RFI2HULK2AKIN10, SNRK1.1MBD9GASA5RGL2MYR2FLKGID1ACOL9FLD, RSI1MIR172CUBP13PIE1LDL2SPL5SPA3BRC1, TCP18VRN1DNFFIE1, FIS3JMJ30TICPHP, CDC73AtBMI1CVIL1, VRN5LWD2ICE1, SCRMSSRP1, HMG, NFDMYB30ARP6, SUF3, ESD1SUS4DCL3ATJ3HDA9JMJ32, JMJD5PUB13LUX, PCL1CDF3REF6, JMJ12UBP26WDR5ALNK2HTA11SMZAGL16INO80AGL18SPL15PIF5, PIL6CKB3LRB2, POB1GID1BHULK3MED12, CCT, CRPFRILIF2LDGA1AtNDXMED16, SFR6CRY1FBH2DET1, FUS2SPT16XAL2, AGL14NF-YB3, HAP3CESD4PHYDFCAVRN2PHYETSFJMJ14, PKDM7B, JMJ4GA2ox8EBSAGL19CAD2, RML1, GSH1AGL24PGI1MOS1GA20ox1FWA, HDG6WRKY34, MSP3ULT1HXK1, GIN2VIP3, SKI8VIL2, VEL1MIR156BSKB1, PRMT5MIR156CATH1CIB1FDAP2MRG1CSP2, GRP2BBX19SHL1, SHLHB16, ATHB16PRR7TFL1ELF6MIR172BSUC9UBP12FTIP1GA20OX3HAM2, HAG5, HAC11FLC, AGL25, FLFMIR156DEMF1MIR156ENF-YA1, HAP2BFYAGL15BAF60, CHC1COFRL1, SUF8RGL3TFL2, LHP1MYR1DCL4HUA2RUP2, EFO2PRR5FPF1MIR156FGID1CPHYCRRP6L2SEF, SWC6RVE2, CIR1VIM3, ORTH1CDF2HLP1ATXR7, SDG25IDD8, NUCGLK2CBP20YAF9A, TAF14B, GAS41CUL4NF-YB2, HAP3BADG1, APS1CIB2LATEPRMT4AEMF2, CYR1GA20ox2PGM1MIR156HZTLVIN3COL5MSI1SRR1PRR3TOE2SIZ1FUL, AGL8HDA5VIP4TOC1LFYFLX4, FLL4BFTCDF1HDA6, RTS1NF-YC4GIS5, EMB2780LNK1HAM1CDKC;2MAF2, AGL31MAF3, AGL70MAF4, AGL69MAF5, AGL68TOE3

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Publications

Seo H S et al., 1995, Plant Mol. Biol.
Silverstone A L et al., 1997, Genetics
Silverstone A L et al., 1998, Plant Cell
Dill A et al., 2001, Genetics
King K E et al., 2001, Genetics
Dill A et al., 2001, Proc. Natl. Acad. Sci. U.S.A.
Silverstone A L et al., 2001, Plant Cell

Appears in the following schemes

Hormone pathway
Gibberellin metabolism
Gibberellin receptors
Aging pathway
Photoperiod pathway

Protein function

Encodes a negative regulator of gibberellin response that belongs to the DELLA family.

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Phenotype

Single mutant:
rga single mutant is slightly early flowering under SD conditions. rga mutation also partially supresses the late flowering-time phenotype of the ga1 single mutant. [Dill et al., 2001][Silverstone et al., 1997]

Multiple mutant:
Mutation of both rga and gai supresses the late flowering of the ga1 single mutant [Cheng et al., 2004]

Overexpressor:
Overexpression of a GA-insensitive version of RGA delays flowering under both SD and LD conditions. Overexpression of the genomic sequence of RGA does not modify the flowering time, except when expressed in phloem tissues. [Galvü¾Œ¶”¼o et al., 2012][Yu et al., 2012]

Function:
Probable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Positively regulates XERICO expression in seeds. Upon GA application, it is degraded by the proteasome, allowing the GA signaling pathway. Compared to other DELLA proteins, it is the most sensitive to GA application. No effect of the BOI proteins on its stability. Its activity is probably regulated by other phytohormones such as auxin and ethylene, attenuation of auxin transport delaying its GA-induced degradation. [Data from UniProt]

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Regulators, targets and interactors

Downstream actors

causality
FT -- [Yu et al., 2012][Porri et al., 2012][Galvo et al., 2012] -- [View TAIR record]

SPL9 -- [Yu et al., 2012][Porri et al., 2012][Galvo et al., 2012] -- [View TAIR record]

MIR172A -- [Galvo et al., 2012] -- [View TAIR record]

LFY -- [Blzquez et al., 2000][Eriksson et al., 2006][Blzquez et al., 1997] -- [View TAIR record]

PIF4 -- [de Lucas et al., 2008] -- [View TAIR record]

SPL5 -- [Yu et al., 2012][Porri et al., 2012][Galvo et al., 2012] -- [View TAIR record]

MIR172C -- [Galvo et al., 2012] -- [View TAIR record]

TSF -- [Porri et al., 2012][Galvo et al., 2012] -- [View TAIR record]

SPL3 -- [Yu et al., 2012][Porri et al., 2012][Galvo et al., 2012] -- [View TAIR record]

MIR172B -- [Galvo et al., 2012] -- [View TAIR record]

AP1 -- [Yamaguchi et al., 2014] -- [View TAIR record]

Upstream actors

causality
GID1A -- [Griffiths et al., 2006][Ariizumi et al., 2008][Nakajima et al., 2006][Silverstone et al., 2001][Peng et al., 1997] -- [View TAIR record]

GID1C -- [Griffiths et al., 2006][Ariizumi et al., 2008][Nakajima et al., 2006][Silverstone et al., 2001][Peng et al., 1997] -- [View TAIR record]

GID1B -- [Griffiths et al., 2006][Ariizumi et al., 2008][Nakajima et al., 2006][Silverstone et al., 2001][Peng et al., 1997] -- [View TAIR record]

Protein-protein interactions

SPL9 -- [Yu et al., 2012][Porri et al., 2012][Galvo et al., 2012] -- [View TAIR record]

PIF4 -- [de Lucas et al., 2008] -- [View TAIR record]

RGA1 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins