Encodes a subunit of the SWR1 complex, which controls H2 acetylation levels.
Multiple mutant: yaf9a
multiple mutant is early flowering under both SD and LD conditions. Those mutations show additive effects on flowering time. [Bieluszewski et al., 2015] Single mutant: yaf9b
single mutant does not display any flowering-time phenotype. [Bieluszewski et al., 2015] Function:
Negative regulator of flowering controlling the H4K5 acetylation levels in the FLC and FT chromatin. Positively regulates FLC expression. Components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of a NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. [Data from UniProt]
Regulators, targets and interactors