Detailed gene information

Genes [306]




ATX1, SDG27
HOMOLOGUE OF TRITHORAX 1 , SET DOMAIN PROTEIN 27
TAIR: AT2G31650
UNIPROT: Q9LJL7
NOWOMICS: View List

Publications

Alvarez-Venegas R et al., 2003, Curr. Biol.
Alvarez-Venegas R et al., 2006, Proc. Natl. Acad. Sci. U.S.A.
Saleh A et al., 2007, Nucleic Acids Res.
Saleh A et al., 2008, Plant Cell
Pien S et al., 2008, Plant Cell
Tamada Y et al., 2009, Plant Cell
Ndamukong I et al., 2009, Plant J.
Ndamukong I et al., 2010, PLoS ONE
Ding Y et al., 2011, Plant Cell
Napsucialy-Mendivil S et al., 2014, J. Exp. Bot.
Berr A et al., 2015, Plant J.

Appears in the following schemes

Time-course regulation of photoperiodic pathway
Mains targets of ABC(E)genes
FLC regulation through protein complexes
General processes & autonomous pathway

Protein function

Encodes a histone methyltransferase involved in the trimethylation of histone H3-lysine 4.

Phenotype

Single mutant:
atx1 single mutant is slightly early flowering under both SD and LD conditions. (The phenotype is stronger in the Ws than in the Col-0 background.) [Pien et al., 2008][Tamada et al., 2009][Shafiq et al., 2014]

Multiple mutant:
atx1;atx2 double mutant and atx1;atxr7 double mutant are early flowering under LD conditions in the Col FRI background. ( No data available under SD conditions.) [Pien et al., 2008][Tamada et al., 2009]

Multiple mutant:
atx1;atxr7 multiple mutant is early flowering under both SD and LD conditions as compared to the atxr7 single mutant. [Tamada et al., 2009]

Remarks:
ATX1 deposits H3K4me3 activating marks at the FLC locus, thus repressing flowering. [Tamada et al., 2009]

Function:
Heterogeneous nuclear ribonucleoprotein (hnRNP)-protein binding the poly(A) tail of mRNA and probably involved in some steps of pre-mRNA maturation. [Data from UniProt]

Regulators, targets and interactors

Downstream actors

causality
FT -- [Shafiq et al., 2014][Berr et al., 2015] -- [View TAIR record]

AG -- [Saleh et al., 2007][Prunet et al., 2008][Carles et al., 2005] -- [View TAIR record]

FLC, AGL25, FLF -- [Pien et al., 2008][Shafiq et al., 2014][Berr et al., 2015] -- [View TAIR record]



Upstream actors


Protein-protein interactions


ATX1, SDG27 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins