Detailed gene information

Genes [306]




SPL3
SQUAMOSA PROMOTER BINDING PROTEIN-LIKE 3
TAIR: AT2G33810
UNIPROT: P93015
NOWOMICS: View List

Publications

Cardon G H et al., 1997, Plant J.
Wu G et al., 2006, Development
Gandikota M et al., 2007, Plant J.
Wu G et al., 2009, Cell
Yamaguchi A et al., 2009, Dev. Cell
Wang J et al., 2009, Cell
Jung J et al., 2011, Plant Mol. Biol.
Kim J J et al., 2012, Plant Physiol.
Jung J et al., 2012, Plant J.

Appears in the following schemes

Overview
Hormone pathway
Aging pathway
Photoperiod pathway
Sugar pathway
Flower development

Protein function

Encodes a SBP-box transcription factor.

Phenotype

Remarks:
SPL3 expression increases in the shoot apical meristem during the photoperiodic induction of flowering. [Schmid et al., 2003]

Remarks:
In Wang et al. (2006), an artificial microRNA downregulating the expression of SPL4 and SPL5 was introduced in a spl3 single mutant background. Transgenic plants have normal plastochron, but there is no mention of the flowering-time phenotype. [Wang et al., 2008]

Overexpressor:
Overexpression of a miR156-resistant version of SPL3 accelerates the transition from the juvenile to the adulte phase and leads to early flowering under both SD and LD conditions. [Wu et al., 2006][Gandikota et al., 2007][Wang et al., 2009][Jung et al., 2011][Kim et al., 2012][Jung et al., 2012][Cardon et al., 1997]

Function:
Trans-acting factor that binds specifically to the consensus nucleotide sequence 5 -TNCGTACAA-3 of AP1 promoter. Binds specifically to the 5 -GTAC-3 core sequence. Promotes both vegetative phase change and flowering. Regulates phase-specific patterns of leaf epidermal differentiation and flowering time, but does not seem to affect leaf shape. [Data from UniProt]

Regulators, targets and interactors

Downstream actors

causality
FUL, AGL8 -- [Wang et al., 2009][Yamaguchi et al., 2009] -- [View TAIR record]

FT -- [Kim et al., 2012] -- [View TAIR record]

AP1 -- [Wang et al., 2009][Yamaguchi et al., 2009] -- [View TAIR record]

LFY -- [Wang et al., 2009][Yamaguchi et al., 2009] -- [View TAIR record]



Upstream actors

causality
FT -- [Jung et al., 2012] -- [View TAIR record]

RGL3 -- [Yu et al., 2012][Porri et al., 2012][Galvão et al., 2012] -- [View TAIR record]

MIR156A -- [Schwab et al., 2006][Gandikota et al., 2007][Wu et al., 2006][Rhoades et al., 2002] -- [View TAIR record]

MIR156D -- [Schwab et al., 2006][Gandikota et al., 2007][Wu et al., 2006][Rhoades et al., 2002] -- [View TAIR record]

MIR156G -- [Schwab et al., 2006][Gandikota et al., 2007][Wu et al., 2006][Rhoades et al., 2002] -- [View TAIR record]

GAI, RGA2 -- [Yu et al., 2012][Porri et al., 2012][Galvão et al., 2012] -- [View TAIR record]

RGL2 -- [Yu et al., 2012][Porri et al., 2012][Galvão et al., 2012] -- [View TAIR record]

SOC1, AGL20 -- [Jung et al., 2012] -- [View TAIR record]

MIR156C -- [Schwab et al., 2006][Gandikota et al., 2007][Wu et al., 2006][Rhoades et al., 2002] -- [View TAIR record]

MIR156F -- [Schwab et al., 2006][Gandikota et al., 2007][Wu et al., 2006][Rhoades et al., 2002] -- [View TAIR record]

SPL9 -- [Schwab et al., 2006][Gandikota et al., 2007][Wu et al., 2006][Rhoades et al., 2002] -- [View TAIR record]

RGL1 -- [Yu et al., 2012][Porri et al., 2012][Galvão et al., 2012] -- [View TAIR record]

FD -- [Jung et al., 2012] -- [View TAIR record]

MIR156B -- [Schwab et al., 2006][Gandikota et al., 2007][Wu et al., 2006][Rhoades et al., 2002] -- [View TAIR record]

MIR156E -- [Schwab et al., 2006][Gandikota et al., 2007][Wu et al., 2006][Rhoades et al., 2002] -- [View TAIR record]

MIR156H -- [Schwab et al., 2006][Gandikota et al., 2007][Wu et al., 2006][Rhoades et al., 2002] -- [View TAIR record]

RGA1 -- [Yu et al., 2012][Porri et al., 2012][Galvão et al., 2012] -- [View TAIR record]



Protein-protein interactions


SPL3 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins