Protein function
Encodes a histone demethylase involved in H3K4me demethylation.
Phenotype
Overexpressor: JMJ15 overexpressor is early flowering under both SD and LD conditions.
[Yang et al., 2012] Single mutant: jmj15 single mutant does not display any flowering-time phenotype.
[Yang et al., 2012] Remarks: JMJ15 is involved in demethylation at the
FLC locus.
[Yang et al., 2012] Function:Histone demethylase that demethylates Lys-4 (H3K4me) of histone H3 with a specific activity for H3K4me3. No activity on H3K4me2, H3K4me1, H3K9me3/2, H3K27me3/2 and H3K36me3/2. Involved in the control of flowering time by demethylating H3K4me3 at the FLC locus and repressing its expression. The repression of FLC level and reduction in H3K4me3 at the FLC locus results in induction of the flowering activator FT, which is a downstream target of FLC.
[Data from UniProt]
Regulators, targets and interactors
Downstream actors
causality FLC, AGL25, FLF --
[Yang et al., 2012] --
[View TAIR record] Upstream actors
Protein-protein interactions