Protein function
Encodes a MYB-domain protein involved in the specification of leaf proximodistal axis.
Phenotype
Single mutant: as1 single mutant is late flowering under SD conditions only.(
as1 single mutant is also late flowering under 12h-light - 12h-dark.)
[Song et al., 2012] Remarks: AS1 interacts with CONSTANS and binds to the promoter of
FT.
[Song et al., 2012] Function:Transcription factor required for normal cell differentiation. Positively regulates LATERAL ORGAN BOUNDARIES (LOB) within the shoot apex, and the class III HD-ZIP genes REV, PHB, and PHV. Interacts directly with ASYMMETRIC LEAVES 2 (LBD6/AS2) to repress the knox homeobox genes BP/KNAT1, KNAT2, and KNAT6 and the abaxial determinants ARF3/ETT, KAN2 and YAB5. May act in parallel with the RDR6-SGS3-AGO7 pathway, an endogenous RNA silencing pathway, to regulate the leaf morphogenesis (PubMed:11076771, PubMed:11140682, PubMed:11882937, PubMed:12750468, PubMed:16006579, PubMed:16699177, PubMed:17395603, PubMed:17559509, PubMed:23271976). Binds directly to KNAT1, KNAT2, and KNATM chromatin, regulating leaf development (PubMed:23271976). LBD6 is required for this binding (PubMed:23271976).
[Data from UniProt]
Regulators, targets and interactors
Downstream actors
causality GA20ox1 --
[Ikezaki et al., 2010][Song et al., 2012] --
[View TAIR record]FT --
[Song et al., 2012] --
[View TAIR record] Upstream actors
Protein-protein interactions
CO --
[Song et al., 2012] --
[View TAIR record]