Detailed gene information

Genes [306]

DCL1LHYGA2ox6MRG2CRY2ATPRMT10ATX2STOESD7, TIL1, ABO4NF-YC9, HAP5CPHYACIB4OTS2LWD1, ATAN11UBC1GAI, RGA2GA3OX1TPLCSTF77ARP4AFR2GIPFT1, MED25TEM1, EDF1CIB5CUL3AVOZ1GA2ox2SUF4FRL2RCD1FBH1GA2ox4CPK33GA2ox7FBH3, AKS1, BHLH122ASH2R, TROHTA9SPA4SPL4RRP6L1NF-YC3HUB2MED13, GCT, MAB2VIM1, ORTH2OTS1, ULP1DVIP5LDL1FTVIM2RGL1AT-STUbl4FKF1, ADO3TEM2, RAV2AP1CDF5CSTF64PHLAFR1SDG26, ASHH1FLM, MAF1, AGL27EFS, SDG8GA2ox1TPS1APL, WDY, FEGA2, ATKS1ELF7PRP8, SUS2, EMB33GA3OX2RGA1UBC2EFMELF8, VIP6ABH1, CBP80CPK6FDP, BZIP27PHYBVIL3, VEL2LKP2MIR156GFVE, MSI4GLK1, GPRI1FIO1GRP7, CCR2MED18SVPAGL17CLF, SDG1SUVR5MIR156AELF3ATCMIR172ATOE1, RAP2.7PUB12FLXUGT87A2ATX1, SDG27COP1SPL3FES1CDF4GA2ox3NF-YA4JMJ15, MEE27SRO1AS1HTA8NF-YB1, HAP3ASNZESD6, HOS1ELF4SPL9FBH4, AKS3VOZ2PIF4FPASDG7, ASSH3CKB4HUB1AHL22AGL6SOC1, AGL20BRM, CHR2LRB1SPA1PRR9CCA1RFI2HULK2AKIN10, SNRK1.1MBD9GASA5RGL2MYR2FLKGID1ACOL9FLD, RSI1MIR172CUBP13PIE1LDL2SPL5SPA3BRC1, TCP18VRN1DNFFIE1, FIS3JMJ30TICPHP, CDC73AtBMI1CVIL1, VRN5LWD2ICE1, SCRMSSRP1, HMG, NFDMYB30ARP6, SUF3, ESD1SUS4DCL3ATJ3HDA9JMJ32, JMJD5PUB13LUX, PCL1CDF3REF6, JMJ12UBP26WDR5ALNK2HTA11SMZAGL16INO80AGL18SPL15PIF5, PIL6CKB3LRB2, POB1GID1BHULK3MED12, CCT, CRPFRILIF2LDGA1AtNDXMED16, SFR6CRY1FBH2DET1, FUS2SPT16XAL2, AGL14NF-YB3, HAP3CESD4PHYDFCAVRN2PHYETSFJMJ14, PKDM7B, JMJ4GA2ox8EBSAGL19CAD2, RML1, GSH1AGL24PGI1MOS1GA20ox1FWA, HDG6WRKY34, MSP3ULT1HXK1, GIN2VIP3, SKI8VIL2, VEL1MIR156BSKB1, PRMT5MIR156CATH1CIB1FDAP2MRG1CSP2, GRP2BBX19SHL1, SHLHB16, ATHB16PRR7TFL1ELF6MIR172BSUC9UBP12FTIP1GA20OX3HAM2, HAG5, HAC11FLC, AGL25, FLFMIR156DEMF1MIR156ENF-YA1, HAP2BFYAGL15BAF60, CHC1COFRL1, SUF8RGL3TFL2, LHP1MYR1DCL4HUA2RUP2, EFO2PRR5FPF1MIR156FGID1CPHYCRRP6L2SEF, SWC6RVE2, CIR1VIM3, ORTH1CDF2HLP1ATXR7, SDG25IDD8, NUCGLK2CBP20YAF9A, TAF14B, GAS41CUL4NF-YB2, HAP3BADG1, APS1CIB2LATEPRMT4AEMF2, CYR1GA20ox2PGM1MIR156HZTLVIN3COL5MSI1SRR1PRR3TOE2SIZ1FUL, AGL8HDA5VIP4TOC1LFYFLX4, FLL4BFTCDF1HDA6, RTS1NF-YC4GIS5, EMB2780LNK1HAM1CDKC;2MAF2, AGL31MAF3, AGL70MAF4, AGL69MAF5, AGL68TOE3

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Publications

Ishitani M et al., 1998, Plant Cell
Lee H et al., 2001, Genes Dev.
Zarka D G et al., 2003, Plant Physiol.
Dong C et al., 2006, Proc. Natl. Acad. Sci. U.S.A.
Lazaro A et al., 2012, Plant Cell
Jung J et al., 2012, J. Biol. Chem.
Lee J H et al., 2012, Plant Cell Physiol.
Lazaro A et al., 2015, Plant Cell

Appears in the following schemes

Photoperiod pathway
Time-course regulation of photoperiodic pathway

Protein function

Encodes an E3 ubiquitin ligase.

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Phenotype

Remarks:
hos1 and phyb mutations have additive effects and the double mutant flowers earlier than either single mutants. [Lü¾Œ–”¼zaro et al., 2015]

Remarks:
hos1 single mutant has reduced FLC expression levels. [Lee et al., 2001]

Single mutant:
hos1 single mutant is late flowering under both SD and LD conditions [Lee et al., 2001][Lü¾Œ–”¼zaro et al., 2012][Jung et al., 2012][Lee et al., 2012][Lü¾Œ–”¼zaro et al., 2015]

Remarks:
HOS1 is involved in the red-light mediated degradation of CO. [Lü¾Œ–”¼zaro et al., 2015]

Function:
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of the transcription factor ICE1. Acts as a negative regulator of cold signaling pathways (PubMed:16702557). Probably involved in recruiting the NUP107-160 subcomplex of the nuclear pore complex to chromatin (Probable). Controls flowering time in response to ambient temperatures (16 and 23 degrees Celsius) and intermittent cold, probably via the regulation of FT and TSF levels (PubMed:22960247). [Data from UniProt]

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Regulators, targets and interactors

Downstream actors

causality
CO -- [Cerdn et al., 2003][Endo et al., 2013][Jung et al., 2012][Lzaro et al., 2012][Lzaro et al., 2015][Valverde et al., 2004][Halliday et al., 2003] -- [View TAIR record]

FT -- [Endo et al., 2013][Endo et al., 2014] -- [View TAIR record]

Upstream actors

causality
PHL -- [Endo et al., 2013][Endo et al., 2014] -- [View TAIR record]

Protein-protein interactions

FVE, MSI4 -- [Lee et al., 2012] -- [View TAIR record]

ESD6, HOS1 -- [Lzaro et al., 2015] -- [View TAIR record]

FLK -- [Lee et al., 2012] -- [View TAIR record]

CO -- [Cerdn et al., 2003][Endo et al., 2013][Jung et al., 2012][Lzaro et al., 2012][Lzaro et al., 2015][Valverde et al., 2004][Halliday et al., 2003] -- [View TAIR record]


PHL -- [Endo et al., 2013][Endo et al., 2014] -- [View TAIR record]

ESD6, HOS1 -- [Lzaro et al., 2015] -- [View TAIR record]

ESD6, HOS1 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins