Protein function
Encodes a protein involved in RNA-mediated chromatin silencing.
Phenotype
Remarks: fpa mutant has increased
FLC expression level. FPA acts together with FCA to prevent the expression of distally polyadenylated antisense RNAs at the
FLC locus.
[Michaels et al., 2001][Duc et al., 2013] Overexpressor: FPA overexpressor is early flowering under SD conditions only. ( Analysis performed in the Ler background).
[Schomburg et al., 2001] Single mutant: fpa single mutant is late flowering under both SD and LD conditions.
[Schomburg et al., 2001][Koornneef et al., 1991][Sanda et al., 1996] Function:Plays a role in the regulation of flowering time in the autonomous flowering pathway by decreasing FLOWERING LOCUS C mRNA levels. Required for RNA-mediated chromatin silencing of a range of loci in the genome. Cotranscriptionally recognizes aberrant RNA and marks it for silencing. Controls alternative cleavage and polyadenylation on pre-mRNAs and antisense RNAs. Acts redundantly with FCA to prevent the expression of distally polyadenylated antisense RNAs at the FLC locus.
[Data from UniProt]
Regulators, targets and interactors
Downstream actors
causality FLC, AGL25, FLF --
[Liu et al., 2010] --
[View TAIR record] Upstream actors
Protein-protein interactions