Protein function
Encodes a component of the circadian clock that belongs to the
PSEUDO-RESPONSE REGULATOR (
PRR) family.
Phenotype
Multiple mutant: prr5;
prr7;
prr9 multiple mutant is late flowering under LD conditions only.
[Nakamichi et al., 2007][Nakamichi et al., 2005] Overexpressor: PRR9 overexpressor is early flowering under both SD and LD conditions. (
PRR9 overexpression results in short circadian clock periods.)
[Matsushika et al., 2002] Function:Transcriptional repressor of CCA1 and LHY, and positive regulator of LWD1 and LWD2 expression. Controls photoperiodic flowering response and temperature compensation. Involved in the positive and negative feedback loops of the circadian clock. Expression of several members of the ARR-like family is controlled by circadian rhythm. Regulated at the transcriptional level by a corepressor complex consisting of ELF4, ELF3, and LUX. APRR9, APRR7, and APRR5 coordinately act on the upstream region of the target genes to repress their expression from noon until midnight. The particular coordinated sequential expression of APRR9, APRR7, APRR5, APRR3 and APPR1 result to circadian waves that may be at the basis of the endogenous circadian clock.
[Data from UniProt]
Regulators, targets and interactors
Downstream actors
causality CCA1 --
[Yamashino et al., 2008][Nakamichi et al., 2010] --
[View TAIR record]TOC1 --
[Wang et al., 2010] --
[View TAIR record]LWD2 --
[Wang et al., 2011] --
[View TAIR record]LWD1, ATAN11 --
[Wang et al., 2011] --
[View TAIR record]LHY --
[Nakamichi et al., 2010] --
[View TAIR record] Upstream actors
causality CCA1 --
[Farré et al., 2005] --
[View TAIR record]TOC1 --
[Huang et al., 2012] --
[View TAIR record]LWD2 --
[Wang et al., 2011] --
[View TAIR record]ELF3 --
[Dixon et al., 2011][Helfer et al., 2011] --
[View TAIR record]LWD1, ATAN11 --
[Wang et al., 2011] --
[View TAIR record]LUX, PCL1 --
[Dixon et al., 2011][Helfer et al., 2011] --
[View TAIR record] Protein-protein interactions