Detailed gene information

Genes [306]




AKIN10, SNRK1.1
ARABIDOPSIS SNF1 KINASE HOMOLOG 10 , SNF1-RELATED PROTEIN KINASE 1.1
TAIR: AT3G01090
UNIPROT: Q38997
NOWOMICS: View List

Publications

Le Guen L et al., 1992, Gene
Farrs R et al., 2001, EMBO J.
Baena-Gonzlez E et al., 2007, Nature
Zhang Y et al., 2009, Plant Physiol.
Jossier M et al., 2009, Plant J.
Fragoso S et al., 2009, Plant Physiol.
Delatte T L et al., 2011, Plant Physiol.
Tsai A Y et al., 2012, Plant J.
Rodrigues A et al., 2013, Plant Cell
Nietzsche M et al., 2014, Front Plant Sci
Jeong E et al., 2015, BMC Plant Biol.
O'Brien M et al., 2015, J. Exp. Bot.
Emanuelle S et al., 2015, Plant J.

Appears in the following schemes

Sugar pathway

Protein function

encodes a subunit of a SNF1-related protein kinase complex.

Phenotype

Overexpressor:
AKIN10 overexpressor is late flowering under LD conditions. ( No data under SD conditions.) [Jeong et al., 2015][Tsai et al., 2012][Baena-Gonzü¾Œ–”¼lez et al., 2007]

Single mutant:
akin10 single mutant does not display any flowering-time phenotype. [Jeong et al., 2015]

Remarks:
AKIN10 physically interacts with IDD8 in the nucleus. This interaction mediates the activity of IDD8 . [Jeong et al., 2015]

Remarks:
The mutation of AKIN10 increases the late flowering-time phenotype of the idd8 mutant. [Jeong et al., 2015]

Function:
Catalytic subunit of the probable trimeric SNF1-related protein kinase (SnRK) complex, which may play a role in a signal transduction cascade regulating gene expression and carbohydrate metabolism in higher plants. The SnRK complex may also be involved in the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase and in assimilation of nitrogen by phosphorylating nitrate reductase. In vitro, KIN10 exhibits kinase activity on sucrose phosphate synthase and the kinase activity is inhibited by PRL1. May be a subunit of a SCF ubiquitin ligase complex and thus be involved in proteasomal ubiquitination. Phosphorylates GRIK1/SNAK2 and GRIK2/SNAK1 in vitro. [Data from UniProt]

Regulators, targets and interactors

Downstream actors

causality
IDD8, NUC -- [Jeong et al., 2015] -- [View TAIR record]

none
PTL -- [O Brien et al., 2015] -- [View TAIR record]

FUS3 -- [Tsai et al., 2012] -- [View TAIR record]



Upstream actors


Protein-protein interactions

IDD8, NUC -- [Jeong et al., 2015] -- [View TAIR record]



AKIN10, SNRK1.1 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins