Detailed gene information

Genes [306]

DCL1LHYGA2ox6MRG2CRY2ATPRMT10ATX2STOESD7, TIL1, ABO4NF-YC9, HAP5CPHYACIB4OTS2LWD1, ATAN11UBC1GAI, RGA2GA3OX1TPLCSTF77ARP4AFR2GIPFT1, MED25TEM1, EDF1CIB5CUL3AVOZ1GA2ox2SUF4FRL2RCD1FBH1GA2ox4CPK33GA2ox7FBH3, AKS1, BHLH122ASH2R, TROHTA9SPA4SPL4RRP6L1NF-YC3HUB2MED13, GCT, MAB2VIM1, ORTH2OTS1, ULP1DVIP5LDL1FTVIM2RGL1AT-STUbl4FKF1, ADO3TEM2, RAV2AP1CDF5CSTF64PHLAFR1SDG26, ASHH1FLM, MAF1, AGL27EFS, SDG8GA2ox1TPS1APL, WDY, FEGA2, ATKS1ELF7PRP8, SUS2, EMB33GA3OX2RGA1UBC2EFMELF8, VIP6ABH1, CBP80CPK6FDP, BZIP27PHYBVIL3, VEL2LKP2MIR156GFVE, MSI4GLK1, GPRI1FIO1GRP7, CCR2MED18SVPAGL17CLF, SDG1SUVR5MIR156AELF3ATCMIR172ATOE1, RAP2.7PUB12FLXUGT87A2ATX1, SDG27COP1SPL3FES1CDF4GA2ox3NF-YA4JMJ15, MEE27SRO1AS1HTA8NF-YB1, HAP3ASNZESD6, HOS1ELF4SPL9FBH4, AKS3VOZ2PIF4FPASDG7, ASSH3CKB4HUB1AHL22AGL6SOC1, AGL20BRM, CHR2LRB1SPA1PRR9CCA1RFI2HULK2AKIN10, SNRK1.1MBD9GASA5RGL2MYR2FLKGID1ACOL9FLD, RSI1MIR172CUBP13PIE1LDL2SPL5SPA3BRC1, TCP18VRN1DNFFIE1, FIS3JMJ30TICPHP, CDC73AtBMI1CVIL1, VRN5LWD2ICE1, SCRMSSRP1, HMG, NFDMYB30ARP6, SUF3, ESD1SUS4DCL3ATJ3HDA9JMJ32, JMJD5PUB13LUX, PCL1CDF3REF6, JMJ12UBP26WDR5ALNK2HTA11SMZAGL16INO80AGL18SPL15PIF5, PIL6CKB3LRB2, POB1GID1BHULK3MED12, CCT, CRPFRILIF2LDGA1AtNDXMED16, SFR6CRY1FBH2DET1, FUS2SPT16XAL2, AGL14NF-YB3, HAP3CESD4PHYDFCAVRN2PHYETSFJMJ14, PKDM7B, JMJ4GA2ox8EBSAGL19CAD2, RML1, GSH1AGL24PGI1MOS1GA20ox1FWA, HDG6WRKY34, MSP3ULT1HXK1, GIN2VIP3, SKI8VIL2, VEL1MIR156BSKB1, PRMT5MIR156CATH1CIB1FDAP2MRG1CSP2, GRP2BBX19SHL1, SHLHB16, ATHB16PRR7TFL1ELF6MIR172BSUC9UBP12FTIP1GA20OX3HAM2, HAG5, HAC11FLC, AGL25, FLFMIR156DEMF1MIR156ENF-YA1, HAP2BFYAGL15BAF60, CHC1COFRL1, SUF8RGL3TFL2, LHP1MYR1DCL4HUA2RUP2, EFO2PRR5FPF1MIR156FGID1CPHYCRRP6L2SEF, SWC6RVE2, CIR1VIM3, ORTH1CDF2HLP1ATXR7, SDG25IDD8, NUCGLK2CBP20YAF9A, TAF14B, GAS41CUL4NF-YB2, HAP3BADG1, APS1CIB2LATEPRMT4AEMF2, CYR1GA20ox2PGM1MIR156HZTLVIN3COL5MSI1SRR1PRR3TOE2SIZ1FUL, AGL8HDA5VIP4TOC1LFYFLX4, FLL4BFTCDF1HDA6, RTS1NF-YC4GIS5, EMB2780LNK1HAM1CDKC;2MAF2, AGL31MAF3, AGL70MAF4, AGL69MAF5, AGL68TOE3

HTML XML JSON

Publications

Hazen S P et al., 2005, Proc. Natl. Acad. Sci. U.S.A.
Onai K et al., 2005, Genes Cells
Edwards K D et al., 2006, Plant Cell
Helfer A et al., 2011, Curr. Biol.

Appears in the following schemes

Temperature pathway
Circadian clock overview

Protein function

Encodes a myb transcription factor involved in the regulation of the circadian clock.

---

Phenotype

Single mutant:
lux single mutant is early flowering under SD conditions.( Conflicting results about the flowering time of lux single mutant under LD conditions) [Hazen et al., 2005][Onai et al., 2005]

Function:
Transcription factor that is essential for the generation of the circadian clock oscillation. Is necessary for activation of CCA1 and LHY expression. Is coregulated with TOC1 and seems to be repressed by CCA1 and LHY by direct binding of these proteins to the evening element in the LUX promoter. Directly regulates the expression of PRR9, a major component of the morning transcriptional feedback circuit, by binding specific sites on PRR9 promoter. Binds to its own promoter, inducing a negative auto-regulatory feedback loop within the core clock. Binds to ELF3 and associates with ELF4 in a diurnal complex which is required for the expression of the growth-promoting transcription factors PIF4 and PIF5 and subsequent hypocotyl growth in the early evening. [Data from UniProt]

---

Regulators, targets and interactors

Downstream actors

causality
PIF4 -- [Dixon et al., 2011][Nozue et al., 2007][Nusinow et al., 2011][Thines et al., 2010][Thines et al., 2014][Mizuno et al., 2014][Yamashino et al., 2003] -- [View TAIR record]

PRR7 -- [Dixon et al., 2011][Helfer et al., 2011] -- [View TAIR record]

ELF4 -- [Helfer et al., 2011][Nusinow et al., 2011] -- [View TAIR record]

GI -- [Helfer et al., 2011][Kolmos et al., 2007] -- [View TAIR record]

LHY -- [Hazen et al., 2005] -- [View TAIR record]

ELF3 -- [Helfer et al., 2011][Nusinow et al., 2011] -- [View TAIR record]

LUX, PCL1 -- [Helfer et al., 2011] -- [View TAIR record]

PIF5, PIL6 -- [Dixon et al., 2011][Nozue et al., 2007][Thines et al., 2010][Thines et al., 2014][Mizuno et al., 2014][Yamashino et al., 2003] -- [View TAIR record]

PRR9 -- [Dixon et al., 2011][Helfer et al., 2011] -- [View TAIR record]

BOA -- [Helfer et al., 2011] -- [View TAIR record]

Upstream actors

causality
TOC1 -- [Huang et al., 2012] -- [View TAIR record]

ELF4 -- [Helfer et al., 2011] -- [View TAIR record]

RVE8 -- [Hsu et al., 2013] -- [View TAIR record]

ELF3 -- [Helfer et al., 2011] -- [View TAIR record]

LUX, PCL1 -- [Helfer et al., 2011] -- [View TAIR record]

LHY -- [Hazen et al., 2005] -- [View TAIR record]

BOA -- [Helfer et al., 2011] -- [View TAIR record]

Protein-protein interactions

ELF3 -- [Helfer et al., 2011][Nusinow et al., 2011] -- [View TAIR record]

ELF4 -- [Helfer et al., 2011][Nusinow et al., 2011] -- [View TAIR record]

LUX, PCL1 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins