Detailed gene information

Genes [306]




SMZ
SCHLAFMUTZE
TAIR: AT3G54990
UNIPROT: Q6PV68
NOWOMICS: View List

Publications

Okamuro J K et al., 1997, Proc. Natl. Acad. Sci. U.S.A.
Schmid M et al., 2003, Development
Jung J et al., 2007, Plant Cell
Mathieu J et al., 2009, PLoS Biol.
Yant L et al., 2010, Plant Cell
Zhu Q et al., 2011, J. Exp. Bot.

Appears in the following schemes

Temperature pathway
Hormone pathway
Aging pathway
Photoperiod pathway
Time-course regulation of photoperiodic pathway
Vernalization

Protein function

Encodes an APETALA2-like transcription factor.

Phenotype

Overexpressor:
SMZ overexpressor is late flowering under both SD and LD conditions. ( The ate-flowering phenotype is stronger under LD conditions.) [Jung et al., 2007][Schmid et al., 2003]

Single mutant:
smz single mutant does not display any flowering-time phenotype. [Mathieu et al., 2009]

Multiple mutant:
smz, snz, toe1, and toe2 mutations have additive effects and lead to an early-flowering phenotype under LD conditions. ( No data available under SD conditions.) [Jung et al., 2012][Mathieu et al., 2009][Yant et al., 2010][Jung et al., 2011]

Remarks:
SMZ protein binds to the promoter of FT to repress its expression. [Mathieu et al., 2009]

Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Repressor of flowering. [Data from UniProt]

Regulators, targets and interactors

Downstream actors

causality
FT -- [Zhang et al., 2015][Jung et al., 2007][Mathieu et al., 2009] -- [View TAIR record]

SMZ -- [Schwab et al., 2005][Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]

TOE2 -- [Schwab et al., 2005][Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]

SOC1, AGL20 -- [Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]

TOE1, RAP2.7 -- [Schwab et al., 2005][Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]

AP2 -- [Schwab et al., 2005][Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]

AP1 -- [Mathieu et al., 2009] -- [View TAIR record]

SNZ -- [Schwab et al., 2005][Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]

TOE3 -- [Schwab et al., 2005][Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]



Upstream actors

causality
MIR172A -- [Jung et al., 2012][Aukerman et al., 2003][Yant et al., 2010][Chen et al., 2004][Schmid et al., 2003][Park et al., 2002] -- [View TAIR record]

AP2 -- [Schwab et al., 2005][Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]

SOC1, AGL20 -- [Immink et al., 2012] -- [View TAIR record]

MIR172C -- [Jung et al., 2012][Aukerman et al., 2003][Yant et al., 2010][Chen et al., 2004][Schmid et al., 2003][Park et al., 2002] -- [View TAIR record]

FLC, AGL25, FLF -- [Deng et al., 2011][Mateos et al., 2015] -- [View TAIR record]

MIR172B -- [Jung et al., 2012][Aukerman et al., 2003][Yant et al., 2010][Chen et al., 2004][Schmid et al., 2003][Park et al., 2002] -- [View TAIR record]

SMZ -- [Schwab et al., 2005][Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]



Protein-protein interactions

TPL -- [Causier et al., 2012][Long et al., 2006][Krogan et al., 2012] -- [View TAIR record]



SMZ interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins