Detailed gene information

Genes [306]

TAIR: AT4G10710


Duroux M et al., 2004, Plant J.
Van Lijsebettens M et al., 2010, Plant Signal Behav
Lolas I B et al., 2010, Plant J.

Appears in the following schemes

FLC regulation through protein complexes
General processes & autonomous pathway

Protein function

Encodes a subunit of the FACT complex, a chromatin remodelling complex involved in the reorganization of nucleosomes.


Single mutant:
spt16 single mutant is early flowering under both SD and LD conditions in terms of days to flowering. However, spt16 single mutant produces more leaves than wild-type plants under SD conditions. [Lolas et al., 2010]

ssrp1 single mutant displays pleiotropic defects and has reduced FLC expression levels. [Lolas et al., 2010]

Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (Probable). [Data from UniProt]

Regulators, targets and interactors

Downstream actors

FLC, AGL25, FLF -- [Lolas et al., 2010] -- [View TAIR record]

Upstream actors

Protein-protein interactions

SPT16 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins