Detailed gene information

Genes [306]

TAIR: AT4G16845


Gendall A R et al., 2001, Cell
Bastow R et al., 2004, Nature
Sheldon C C et al., 2006, Plant J.
De Lucia F et al., 2008, Proc. Natl. Acad. Sci. U.S.A.
Sheldon C C et al., 2009, Plant J.

Appears in the following schemes

FLC regulation through protein complexes

Protein function

Encodes a DNA-binding protein involved in the repression of FLC expression.


Single mutant:
vrn2 single mutant does not display any flowering-time phenotype. However, vrn2 single mutant suppresses Col FRI response to vernalization. [Gendall et al., 2001]

Multiple mutant:
vrn2;fca double mutant is late flowering under both SD and LD conditions and display increased FLC expression levels. [Sheldon et al., 2000]

VRN2 is involved in the maintenance of FLC repression after a cold treatment. [Gendall et al., 2001]

Polycomb group (PcG) protein. Plays a central role in vernalization by maintaining repressed the homeotic gene FLC, a floral repressor, after a cold treatment. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility. Associates constitutively along the whole FLC locus. [Data from UniProt]

Regulators, targets and interactors

Downstream actors

Upstream actors

Protein-protein interactions

FIE1, FIS3 -- [Wood et al., 2006] -- [View TAIR record]

VIN3 -- [Wood et al., 2006] -- [View TAIR record]

CLF, SDG1 -- [Wood et al., 2006][Chanvivattana et al., 2004] -- [View TAIR record]

VIL1, VRN5 -- [De Lucia et al., 2008] -- [View TAIR record]

SWN -- [Wood et al., 2006][Chanvivattana et al., 2004] -- [View TAIR record]

VRN2 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins