Detailed gene information

Genes [306]




TSF
TWIN SISTER OF FT
TAIR: AT4G20370
UNIPROT: Q9S7R5
NOWOMICS: View List

Publications

Michaels S D et al., 2005, Plant Physiol.
Yamaguchi A et al., 2005, Plant Cell Physiol.
Mathieu J et al., 2007, Curr. Biol.
Jang S et al., 2009, Plant J.
D'Aloia M et al., 2011, Plant J.
Ando E et al., 2013, Plant Physiol.
Hiraoka K et al., 2013, Plant Cell Physiol.
Jin S et al., 2015, J. Exp. Bot.

Appears in the following schemes

Overview
Temperature pathway
Hormone pathway
Photoperiod pathway
Flower development

Protein function

Encodes a transcription factor from the phosphatidylethanolamine-binding protein (PEBP) family.

Phenotype

Multiple mutant:
tsf mutation enhance the late-flowering phenotype of the ft mutant under LD conditions. (Conflicting results under SD conditions.) [Jang et al., 2009][Michaels et al., 2005][Yamaguchi et al., 2005]

Overexpressor:
TSF overexpressor is early flowering under both SD and LD conditions. [Michaels et al., 2005][Yamaguchi et al., 2005]

Single mutant:
tsf single mutant does not display any flowering-time phenotype under LD conditions. (Conflicting results under SD conditions.) [Michaels et al., 2005][Yamaguchi et al., 2005]

Remarks:
Micrografting experiments of different Arabidopsis genotypes showed that TSF protein has a lower protein mobility than FT. [Jin et al., 2015]

Function:
May form complexes with phosphorylated ligands by interfering with kinases and their effectors. [Data from UniProt]

Regulators, targets and interactors

Downstream actors

causality
SOC1, AGL20 -- [Yamaguchi et al., 2005][Jang et al., 2009] -- [View TAIR record]



Upstream actors

causality
GAI, RGA2 -- [Porri et al., 2012][Galvão et al., 2012] -- [View TAIR record]

RGL2 -- [Porri et al., 2012][Galvão et al., 2012] -- [View TAIR record]

TEM2, RAV2 -- [Castillejo et al., 2008][Osnato et al., 2012][Marín-González et al., 2015] -- [View TAIR record]

RGL1 -- [Porri et al., 2012][Galvão et al., 2012] -- [View TAIR record]

TEM1, EDF1 -- [Castillejo et al., 2008][Osnato et al., 2012][Marín-González et al., 2015] -- [View TAIR record]

RGA1 -- [Porri et al., 2012][Galvão et al., 2012] -- [View TAIR record]

RGL3 -- [Porri et al., 2012][Galvão et al., 2012] -- [View TAIR record]

CO -- [Yamaguchi et al., 2005][Yoo et al., 2005][Ben-Naim et al., 2006][Tiwari et al., 2010][Samach et al., 2000][Kardailsky et al., 1999][Kobayashi et al., 1999] -- [View TAIR record]



Protein-protein interactions

FDP, BZIP27 -- [Jang et al., 2009] -- [View TAIR record]

BRC1, TCP18 -- [Niwa et al., 2013] -- [View TAIR record]

FD -- [Jang et al., 2009] -- [View TAIR record]



TSF interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins