Detailed gene information

Genes [306]




JMJ14, PKDM7B, JMJ4
JUMONJI 14 , PKDM7B , JUMONJI 4
TAIR: AT4G20400
UNIPROT: Q8GUI6
NOWOMICS: View List

Publications

Jeong J et al., 2009, PLoS ONE
Lu F et al., 2010, Cell Res.
Searle I R et al., 2010, Genes Dev.
Le Masson I et al., 2012, Plant Cell

Appears in the following schemes

Time-course regulation of photoperiodic pathway
General processes & autonomous pathway

Protein function

Encodes a H3K4 demethylase that represses the expression of FT and TSF.

Phenotype

Single mutant:
jmj14 single mutant is early flowering under both SD and LD conditions. [Lu et al., 2010][Yang et al., 2010][Jeong et al., 2009][Searle et al., 2010]

Remarks:
JMJ14 represses the expression of FT and TSF. [Lu et al., 2010][Yang et al., 2010][Jeong et al., 2009]

Function:
Histone demethylase that demethylates Lys-4 (H3K4me) of histone H3 with a higher activity for H3K4me3 and H3K4me2 than H3K4me1. No activity on H3K9me3/2, H3K36me3/2 and H3K27me3/2. Represses FT and TSF expression to inhibit the floral transition. Binds around the transcription start site of the FT locus. Involved in the DRM2-mediated maintenance of DNA methylation, but not required for the de novo DNA methylation. Required for demethylating histone H3K4me3 at the target of RNA silencing. [Data from UniProt]

Regulators, targets and interactors

Downstream actors

causality
FT -- [Lu et al., 2010][Yang et al., 2010][Jeong et al., 2009] -- [View TAIR record]



Upstream actors


Protein-protein interactions

AtBMI1B, DRIP1 -- [Wang et al., 2014] -- [View TAIR record]

AtBMI1A, DRIP2 -- [Wang et al., 2014] -- [View TAIR record]

NAC050 -- [Ning et al., 2015] -- [View TAIR record]

NAC052 -- [Ning et al., 2015] -- [View TAIR record]



JMJ14, PKDM7B, JMJ4 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins