Detailed gene information

Genes [306]




GA2ox8
GIBBERELLIN 2-OXIDASE 8
TAIR: AT4G21200
UNIPROT: O49561
NOWOMICS: View List

Publications

Schomburg F M et al., 2003, Plant Cell
Zhao X et al., 2007, Plant Physiol.

Appears in the following schemes

Hormone pathway
Photoperiod pathway

Protein function

Encodes an oxidase involved in the catabolism of bioactive gibberellins.

Phenotype

Overexpressor:
GA20X8 overexpressor is late flowering under both SD and LD conditions. ( Plants are dwarfed and show pleiotropic defects. The flowering-time phenotype is stronger under SD conditions.) [Schomburg et al., 2003]

Multiple mutant:
ga2ox7;8 multiple mutant is early flowering under both SD and LD conditions. [Schomburg et al., 2003]

Single mutant:
ga2ox8 single mutant is early flowering under SD conditions only. [Schomburg et al., 2003]

Function:
Catalyzes the 2-beta-hydroxylation of gibberellins (GA) precursors, rendering them unable to be converted to active GAs. Hydroxylates the C20-GA GA12 and GA53, but is not active on C19-GAs, like GA1, GA4, GA9 and GA20. [Data from UniProt]

Regulators, targets and interactors

Downstream actors


Upstream actors


Protein-protein interactions


GA2ox8 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins