Detailed gene information

Genes [306]




GA20ox1
GIBBERELLIN 20-OXIDASE 1
TAIR: AT4G25420
UNIPROT: Q39110
NOWOMICS: View List

Publications

Talon M et al., 1990, Proc. Natl. Acad. Sci. U.S.A.
Kobayashi M et al., 1994, Plant Physiol.
Xu Y L et al., 1995, Proc. Natl. Acad. Sci. U.S.A.
Coles J P et al., 1999, Plant J.
Rieu I et al., 2008, Plant J.
Mauriat M et al., 2009, Plant J.
Plackett A R G et al., 2012, Plant Cell
Barboza L et al., 2013, Proc. Natl. Acad. Sci. U.S.A.

Appears in the following schemes

Hormone pathway
Gibberellin metabolism
Photoperiod pathway

Protein function

Encodes an oxidase involved in the conversion of inactive gibberellins to their bioactive form.

Phenotype

Overexpressor:
GA20OX1 overexpressor is early flowering under both SD and LD conditions. [Coles et al., 1999][Rieu et al., 2008]

Single mutant:
ga20ox1 single mutant does not display any flowering-time phenotype. [Rieu et al., 2008]

Multiple mutant:
ga20ox1;ga20ox2 multiple mutant is late flowering under both SD and LD conditions. [Rieu et al., 2008]

Function:
Key oxidase enzyme in the biosynthesis of gibberellin that catalyzes the conversion of GA12 and GA53 to GA9 and GA20 respectively, via a three-step oxidation at C-20 of the GA skeleton. GA53 is less effectively oxidized than GA12, and GA25 is also formed as a minor product. Involved in the promotion of the floral transition, fertiliy and silique elongation, but plays only a minor role in elongation of seedling organs. Acts redundantly with GA20OX2. [Data from UniProt]

Regulators, targets and interactors

Downstream actors


Upstream actors

causality
AS1 -- [Ikezaki et al., 2010][Song et al., 2012] -- [View TAIR record]

MYR1 -- [Zhao et al., 2011] -- [View TAIR record]

TEM2, RAV2 -- [Osnato et al., 2012] -- [View TAIR record]

TEM1, EDF1 -- [Osnato et al., 2012] -- [View TAIR record]

MYR2 -- [Zhao et al., 2011] -- [View TAIR record]



Protein-protein interactions


GA20ox1 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins