Detailed gene information

Genes [306]




HXK1, GIN2
HEXOKINASE 1, GLUCOSE INSENSITIVE 2
TAIR: AT4G29130
UNIPROT: Q42525
NOWOMICS: View List

Publications

Jang J C et al., 1997, Plant Cell
Moore B et al., 2003, Science
Cho Y et al., 2006, Cell

Appears in the following schemes

Aging pathway
Sugar pathway

Protein function

Encodes an enzyme involved in fructose and glucose phosphorylation.

Phenotype

Single mutant:
hkx1 single mutant is late flowering under SD conditions only.( Analysis performed in the Ler background. hkx1 single mutant shows pleiotropic defects. ) [Matsoukas et al., 2013][Moore et al., 2003]

Function:
Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells. [Data from UniProt]

Regulators, targets and interactors

Downstream actors


Upstream actors


Protein-protein interactions


HXK1, GIN2 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins