Protein function
Encodes a transcription factor that negatively regulates the expression of the C class floral homeotic genes.
Phenotype
Single mutant: leunig single mutant has homeotic defects in the two outer whorls of the flower.
[Liu et al., 1995] Multiple mutant: seuss;
leunig double mutant shows enhanced homeotic floral defects.
[Franks et al., 2002][Sridhar et al., 2004] Remarks: LEUNIG is required for the repression of
AGAMOUS expression during flower development.
[Liu et al., 1995] Remarks: LEUNIG, together with SEUSS, regulates the expression of
MIR172. LEUNIG and SEUSS were shown to interact both
in vitro and
in vivo.
[Grigorova et al., 2011][Sridhar et al., 2004] Function:Transcription repressor subunit of the SEU-LUG transcriptional corepressor of the C class floral homeotic gene AGAMOUS during the early stages of floral meristem development. Is part of the A class cadastral complex that define the boundaries between the A and C class homeotic genes expression and function. Interacts together with APETALA2 and SEUSS to repress AGAMOUS expression. Also plays a role in ovule and pollen development (PubMed:11782418, PubMed:15277686, PubMed:7743940). Implicated in embryo and floral development (PubMed:18390806). Involved in post-synthesis cell wall modifications necessary for mucilage extrusion from seeds upon imbibition, probably by promoting the expression of genes required for mucilage maturation (PubMed:21362134, PubMed:21402796). Involved in vegetative leaf morphogenesis at later stages of leaf development by restricting cell expansion during leaf growth (PubMed:15208345). Regulates the maintenance on leaf polarity and meristem activity as well as the initiation of embryonic shoot apical meristem (SAM) development (PubMed:19837869).
[Data from UniProt]
Regulators, targets and interactors
Downstream actors
causality AG --
[Conner et al., 2000][Sridhar et al., 2006][Kaufmann et al., 2009][Franks et al., 2002] --
[View TAIR record] Upstream actors
Protein-protein interactions
SEP3 --
[Sridhar et al., 2006] --
[View TAIR record]AP1 --
[Sridhar et al., 2006] --
[View TAIR record] SEP3 --
[Conner et al., 2000][Sridhar et al., 2006][Franks et al., 2002] --
[View TAIR record]SEU --
[Sridhar et al., 2006] --
[View TAIR record]AP1 --
[Conner et al., 2000][Sridhar et al., 2006][Smaczniak et al., 2012][Franks et al., 2002] --
[View TAIR record]