Detailed gene information

Genes [306]

TAIR: AT4G32551


Liu Z et al., 1995, Development
Sieburth L E et al., 1997, Plant Cell
Chen C et al., 2000, Genesis
Conner J et al., 2000, Proc. Natl. Acad. Sci. U.S.A.
Liu Z et al., 2000, Plant Cell
Franks R G et al., 2006, Planta
Gonzalez D et al., 2007, Mol. Cell. Biol.
Sitaraman J et al., 2008, Plant Physiol.
Stahle M I et al., 2009, Plant Cell
Grigorova B et al., 2011, Development
Walker M et al., 2011, Plant Physiol.

Appears in the following schemes

Mains targets of ABC(E)genes

Protein function

Encodes a transcription factor that negatively regulates the expression of the C class floral homeotic genes.


Single mutant:
leunig single mutant has homeotic defects in the two outer whorls of the flower. [Liu et al., 1995]

Multiple mutant:
seuss;leunig double mutant shows enhanced homeotic floral defects. [Franks et al., 2002][Sridhar et al., 2004]

LEUNIG is required for the repression of AGAMOUS expression during flower development. [Liu et al., 1995]

LEUNIG, together with SEUSS, regulates the expression of MIR172. LEUNIG and SEUSS were shown to interact both in vitro and in vivo. [Grigorova et al., 2011][Sridhar et al., 2004]

Transcription repressor subunit of the SEU-LUG transcriptional corepressor of the C class floral homeotic gene AGAMOUS during the early stages of floral meristem development. Is part of the A class cadastral complex that define the boundaries between the A and C class homeotic genes expression and function. Interacts together with APETALA2 and SEUSS to repress AGAMOUS expression. Also plays a role in ovule and pollen development (PubMed:11782418, PubMed:15277686, PubMed:7743940). Implicated in embryo and floral development (PubMed:18390806). Involved in post-synthesis cell wall modifications necessary for mucilage extrusion from seeds upon imbibition, probably by promoting the expression of genes required for mucilage maturation (PubMed:21362134, PubMed:21402796). Involved in vegetative leaf morphogenesis at later stages of leaf development by restricting cell expansion during leaf growth (PubMed:15208345). Regulates the maintenance on leaf polarity and meristem activity as well as the initiation of embryonic shoot apical meristem (SAM) development (PubMed:19837869). [Data from UniProt]

Regulators, targets and interactors

Downstream actors

AG -- [Conner et al., 2000][Sridhar et al., 2006][Kaufmann et al., 2009][Franks et al., 2002] -- [View TAIR record]

Upstream actors

Protein-protein interactions

SEP3 -- [Sridhar et al., 2006] -- [View TAIR record]

AP1 -- [Sridhar et al., 2006] -- [View TAIR record]

SEP3 -- [Conner et al., 2000][Sridhar et al., 2006][Franks et al., 2002] -- [View TAIR record]

SEU -- [Sridhar et al., 2006] -- [View TAIR record]

AP1 -- [Conner et al., 2000][Sridhar et al., 2006][Smaczniak et al., 2012][Franks et al., 2002] -- [View TAIR record]

LUG interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins