Detailed gene information

Genes [306]




AP2
APETALA2
TAIR: AT4G36920
UNIPROT: P47927
NOWOMICS: View List

Publications

Bowman J L et al., 1989, Plant Cell
Drews G N et al., 1991, Cell
Jack T et al., 1994, Cell
Jofuku K D et al., 1994, Plant Cell
Weigel D et al., 1995, Plant Cell
Wilson K et al., 1996, Plant Cell
Okamuro J K et al., 1997, Proc. Natl. Acad. Sci. U.S.A.
Finkelstein R R et al., 1998, Plant Cell
Aukerman M J et al., 2003, Plant Cell
Chen X et al., 2004, Science

Appears in the following schemes

Aging pathway
Photoperiod pathway
Time-course regulation of photoperiodic pathway
Flower development
Mains targets of ABC(E)genes
Kinetics of ABC(E) genes expression
Specification of flower meristems

Protein function

Encodes a MADS-box transcription factor.

Phenotype

Overexpressor:
AP2 overexpressor is slightly late flowering under LD conditions.(No data available under SD conditions.) [Chen et al., 2004]

Single mutant:
ap2 single mutant is early flowering under both SD and LD conditions and shows abnormal flower development: sepals are converted into ovule-bearing carpels. [Yant et al., 2010][Drews et al., 1991][Bowman et al., 1989]

Function:
Probable transcriptional activator that promotes early floral meristem identity. Is required subsequently for the transition of an inflorescence meristem into a floral meristem. Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower. Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors like LEUNIG and SEUSS. It is also required during seed development. [Data from UniProt]

Regulators, targets and interactors

Downstream actors

causality
MIR172A -- [Yant et al., 2010] -- [View TAIR record]

MIR156H -- [Yant et al., 2010] -- [View TAIR record]

SOC1, AGL20 -- [Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]

TOE1, RAP2.7 -- [Schwab et al., 2005][Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]

AP1 -- [Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]

AP2 -- [Schwab et al., 2005][Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]

MIR156A -- [Yant et al., 2010] -- [View TAIR record]

MIR156D -- [Yant et al., 2010] -- [View TAIR record]

MIR156G -- [Yant et al., 2010] -- [View TAIR record]

MIR172C -- [Yant et al., 2010] -- [View TAIR record]

SNZ -- [Schwab et al., 2005][Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]

SEP3 -- [Yant et al., 2010][Krogan et al., 2012] -- [View TAIR record]

TOE3 -- [Schwab et al., 2005][Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]

ARF3, ETT -- [Yant et al., 2010] -- [View TAIR record]

MIR156C -- [Yant et al., 2010] -- [View TAIR record]

MIR156F -- [Yant et al., 2010] -- [View TAIR record]

MIR172B -- [Yant et al., 2010] -- [View TAIR record]

SMZ -- [Schwab et al., 2005][Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]

AG -- [Yant et al., 2010][Krogan et al., 2012][Drews et al., 1991][Bowman et al., 1991] -- [View TAIR record]

TOE2 -- [Schwab et al., 2005][Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]

AGL15 -- [Yant et al., 2010] -- [View TAIR record]

AP3 -- [Krogan et al., 2012] -- [View TAIR record]

MIR156B -- [Yant et al., 2010] -- [View TAIR record]

MIR156E -- [Yant et al., 2010] -- [View TAIR record]



Upstream actors

causality
AP2 -- [Schwab et al., 2005][Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]

MIR172A -- [Jung et al., 2012][Aukerman et al., 2003][Yant et al., 2010][Chen et al., 2004][Schmid et al., 2003][Wollmann et al., 2010][Park et al., 2002] -- [View TAIR record]

PNY, RPL, BLR -- [Smaczniak et al., 2012] -- [View TAIR record]

LFY -- [Liu et al., 2009] -- [View TAIR record]

MIR172C -- [Jung et al., 2012][Aukerman et al., 2003][Yant et al., 2010][Chen et al., 2004][Schmid et al., 2003][Wollmann et al., 2010][Park et al., 2002] -- [View TAIR record]

SMZ -- [Schwab et al., 2005][Yant et al., 2010][Mathieu et al., 2009] -- [View TAIR record]

MIR172B -- [Jung et al., 2012][Aukerman et al., 2003][Yant et al., 2010][Chen et al., 2004][Schmid et al., 2003][Wollmann et al., 2010][Park et al., 2002] -- [View TAIR record]

AP1 -- [Smaczniak et al., 2012] -- [View TAIR record]



Protein-protein interactions

TPL -- [Krogan et al., 2012] -- [View TAIR record]



AP2 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins