Encodes an acetyltransferase mainly involved in the acetylation of histone H4K5.
Multiple mutant: ham1
double heterozygous mutant is early flowering under LD conditions. ( No data under SD conditions.) [Xiao et al., 2013] Remarks: ham1
homozygous double mutant is lethal. [Latrasse et al., 2008] Artificial microRNA:
Artificial microRNA downregulation of both HAM1
leads to early flowering under both SD and LD conditions [Xiao et al., 2013] Function:
Histone acetyltransferase which may be involved in transcriptional activation. Acetylates Lys-5 of histone H4 (H4K5ac) (PubMed:16648464, PubMed:17877703). Essential for gametophyte development (PubMed:19040736). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925). [Data from UniProt]
Regulators, targets and interactors