Protein function
Encodes an acetyltransferase mainly involved in the acetylation of histone H4K5.
Phenotype
Multiple mutant: ham1;
ham2 double heterozygous mutant is early flowering under LD conditions. ( No data under SD conditions.)
[Xiao et al., 2013] Remarks: ham1;
ham2 homozygous double mutant is lethal.
[Latrasse et al., 2008] Artificial microRNA: Artificial microRNA downregulation of both
HAM1 and
HAM2 leads to early flowering under both SD and LD conditions
[Xiao et al., 2013] Function:Histone acetyltransferase which may be involved in transcriptional activation. Acetylates Lys-5 of histone H4 (H4K5ac) (PubMed:16648464, PubMed:17877703). Essential for gametophyte development (PubMed:19040736). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925).
[Data from UniProt]
Regulators, targets and interactors
Downstream actors
Upstream actors
Protein-protein interactions