Detailed gene information

Genes [306]




RUP2, EFO2
REPRESSOR OF UV-B PHOTOMORPHOGENESIS 2, EARLY FLOWERING BY OVEREXPRESSION 2
TAIR: AT5G23730
UNIPROT: Q9FFA7
NOWOMICS: View List

Publications

Gruber H et al., 2010, Proc. Natl. Acad. Sci. U.S.A.
Wang W et al., 2011, J. Exp. Bot.
Heijde M et al., 2013, Proc. Natl. Acad. Sci. U.S.A.
Heijde M et al., 2013, Proc. Natl. Acad. Sci. U.S.A.
Ouyang X et al., 2014, Proc. Natl. Acad. Sci. U.S.A.
Yin R et al., 2015, Plant Cell

Appears in the following schemes

Photoperiod pathway

Protein function

Encodes a repressor of UV-B photomorphogenesis.

Phenotype

Remarks:
co mutation supresses the early-flowering phenotype of efo2 single mutant. EFO2 expression is circadian clock-regulated. [Wang et al., 2011]

Multiple mutant:
efo1;efo2 multiple mutant shows additive effects on multiple developmental aspects (rosette size, hypocotyl length, etc.), but not flowering time. efo1;efo2 multiple mutant flowers later than efo2 single mutant. [Wang et al., 2011]

Overexpressor:
EFO2 overexpressor is early flowering under both SD and LD conditions. [Wang et al., 2011]

Single mutant:
efo2 single mutant is early flowering under SD conditions. [Wang et al., 2011]

Function:
Functions in association with RUP1 as repressor of UV-B-induced photomorphogenesis mediated by UVR8 and HY5. Plays a crucial negative feedback regulatory role downstream of UVR8-COP1 to inhibit UVR8 function, balance UV-B-specific responses and ensure normal plant growth. Is involved in the regulation of photoperiodic flowering and vegetative development. May act as negative regulator of photoperiodic flowering by suppressing flowering through the action of CONSTANS (CO) and FLOWERING LOCUS T (FT). [Data from UniProt]

Regulators, targets and interactors

Downstream actors

causality
CO -- [Wang et al., 2011] -- [View TAIR record]



Upstream actors


Protein-protein interactions


RUP2, EFO2 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins