Protein function
Encodes a zinc finger transcription factor.
Phenotype
Multiple mutant: cdf1;
cdf2;
cdf3;
cdf5 quadruple mutant is early flowering under both SD and LD conditions, with additive effects. ( In this multiple mutant,
CDF1 is downregulated by RNAi while other
cdf mutants are null mutants.)
[Fornara et al., 2009] Single mutant: cdf2 single mutant is early flowering under both SD and LD conditions.
[Fornara et al., 2009] Remarks: GI acts through
CDFs to regulate the expression of
CO and
FT, but CDFs are also involved in the regulation of additional processes which are not related to the control of flowering-time. GI also has CDF-independent functions - e.g. in the circadian clock.
[Fornara et al., 2015] Remarks: The overexpression of
CDF2 leads to conflicting results: Imaizumi et al. (2005) did not observe a flowering-time phenotype while Fornara et al. (2009) observed an early flowering time in LD when
CFD2 was overexpressed in the vasculature (
SUC2 promoter).
[Fornara et al., 2009][Imaizumi et al., 2005] Function:Transcription factor that binds specifically to a 5 -AA[AG]G-3 consensus core sequence (By similarity). Regulates a photoperiodic flowering response. Transcriptional repressor of CONSTANS expression. The stability of CDF2 is controlled by GIGANTEA and redundantly by ADO3, ADO2 and/or ADO1.
[Data from UniProt]
Regulators, targets and interactors
Downstream actors
causality FT --
[Song et al., 2012] --
[View TAIR record]CO --
[Fornara et al., 2009][Rosas et al., 2014][Imaizumi et al., 2005][Sawa et al., 2007] --
[View TAIR record] Upstream actors
causality GI --
[Fornara et al., 2009][Kim et al., 2007][Imaizumi et al., 2005][Sawa et al., 2007] --
[View TAIR record]AT-STUbl4 --
[Elrouby et al., 2013] --
[View TAIR record]LKP2 --
[Fornara et al., 2009][Kim et al., 2007] --
[View TAIR record]FKF1, ADO3 --
[Fornara et al., 2009][Imaizumi et al., 2005][Sawa et al., 2007] --
[View TAIR record] Protein-protein interactions
LKP2 --
[Imaizumi et al., 2005] --
[View TAIR record] GI --
[Fornara et al., 2009][Kim et al., 2007][Imaizumi et al., 2005][Sawa et al., 2007] --
[View TAIR record]FKF1, ADO3 --
[Fornara et al., 2009][Imaizumi et al., 2005][Sawa et al., 2007] --
[View TAIR record]