Protein function
Encodes a transcription repressor participating in the polycomb group (PcG) protein complex-mediated silencing of flower homeotic genes.
Phenotype
Single mutant: emf2 single mutant is extremely early flowering under both SD and LD conditions.
[Yang et al., 1995][Haung et al., 1998] Overexpressor: Overexpression of sense EMF2 transcripts does not lead to any flowering-time phenotype.
[Yoshida et al., 2001] RNA interference: RNAi downregulation of EMF2 leads to an early flowering phenotype under both SD and LD conditions.
[Yoshida et al., 2001] Function:Polycomb group (PcG) protein. Involved in flowering processes by repressing unknown target genes and preventing reproductive development. Participates in polycomb group (PcG) protein complex-mediated (probably in complex with EMF1) silencing of the flower homeotic genes AGAMOUS (AG), PISTILLATA (PI), and APETALA3 (AP3), as well as of some regulatory genes such as ABSCISIC ACID INSENSITIVE3 (ABI3), LONG VEGETATIVE PHASE1 (LOV1), and FLOWERING LOCUS C (FLC) during vegetative development, by mediating trimethylation of histone 3 lysine 27 on the AG chromatin (H3K27me3). PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility.
[Data from UniProt]
Regulators, targets and interactors
Downstream actors
causality AG --
[Goodrich et al., 1997][Kinoshita et al., 2001][Chen et al., 1997][Hennig et al., 2003] --
[View TAIR record]AGL19 --
[Schönrock et al., 2006] --
[View TAIR record] Upstream actors
Protein-protein interactions
CLF, SDG1 --
[Chanvivattana et al., 2004] --
[View TAIR record]SWN --
[Chanvivattana et al., 2004] --
[View TAIR record]