Detailed gene information

Genes [306]




LFY
LEAFY
TAIR: AT5G61850
UNIPROT: Q00958
NOWOMICS: View List

Publications

Schultz E A et al., 1991, Plant Cell
Weigel D et al., 1992, Cell
Weigel D et al., 1995, Nature
Blzquez M A et al., 1997, Development
William D A et al., 2004, Proc. Natl. Acad. Sci. U.S.A.
Eriksson S et al., 2006, Plant Cell
Lee J et al., 2008, Plant J.
Hams C et al., 2008, EMBO J.
Sayou C et al., 2014, Science

Appears in the following schemes

Overview
Temperature pathway
Hormone pathway
Aging pathway
Photoperiod pathway
Sugar pathway
Flower development
Mains targets of ABC(E)genes
Kinetics of ABC(E) genes expression
Specification of flower meristems
Vernalization

Protein function

Encodes a transcription factor involved in the establishment of floral meristem identity.

Phenotype

Overexpressor:
LEAFY overexpressor is slightly early flowering under both SD and LD conditions. The primary shoots of LEAFY overexpressor is converted in a terminal flower. [Weigel et al., 1995][Ferrü¾Œ–”¼ndiz et al., 2000][Blü¾Œ–”¼zquez et al., 1997]

Single mutant:
leafy single mutant has partial transformation of lateral flower meristems into inflorescence branches. [Weigel et al., 1992][Mandel et al., 1992][Jofuku et al., 1994][Kempin et al., 1995][Ingram et al., 1995]

Function:
Probable transcription factor that promotes early floral meristem identity in synergy with APETALA1. Is required subsequently for the transition of an inflorescence meristem into a floral meristem, by an immediate upstream regulation of the ABC classes of floral homeotic genes. Activates directly APETALA1, CAULIFLOWER and AGAMOUS, and indirectly APETALA3 and PISTILLATA with the cooperation of UFO. [Data from UniProt]

Regulators, targets and interactors

Downstream actors

causality
CAL -- [William et al., 2004] -- [View TAIR record]

FD -- [Winter et al., 2011] -- [View TAIR record]

SPL4 -- [Winter et al., 2011] -- [View TAIR record]

FUL, AGL8 -- [Winter et al., 2011] -- [View TAIR record]

AP1 -- [Liu et al., 2009][Winter et al., 2011][Grandi et al., 2012][Wagner et al., 1999] -- [View TAIR record]

TOE3 -- [Winter et al., 2011] -- [View TAIR record]

AP3 -- [Chae et al., 2008] -- [View TAIR record]

TFL1 -- [Winter et al., 2011][Parcy et al., 2002] -- [View TAIR record]

SPL11 -- [Winter et al., 2011] -- [View TAIR record]

LFY -- [Winter et al., 2011] -- [View TAIR record]

TEM1, EDF1 -- [Winter et al., 2011] -- [View TAIR record]

AG -- [Liu et al., 2009][Lenhard et al., 2001][Lohmann et al., 2001] -- [View TAIR record]

FDP, BZIP27 -- [Winter et al., 2011] -- [View TAIR record]

SPL5 -- [Winter et al., 2011] -- [View TAIR record]

NF-YB2, HAP3B -- [Winter et al., 2011] -- [View TAIR record]

LMI2, MYB17 -- [Winter et al., 2011][William et al., 2004] -- [View TAIR record]

AP2 -- [Liu et al., 2009] -- [View TAIR record]



Upstream actors

causality
SOC1, AGL20 -- [Immink et al., 2012][Lee et al., 2008][Dorca-Fornell et al., 2011][Liu et al., 2008][Michaels et al., 2003] -- [View TAIR record]

LMI2, MYB17 -- [Pastore et al., 2011] -- [View TAIR record]

SPL5 -- [Wang et al., 2009][Yamaguchi et al., 2009] -- [View TAIR record]

GAI, RGA2 -- [Blzquez et al., 2000][Eriksson et al., 2006][Blzquez et al., 1997] -- [View TAIR record]

RGL2 -- [Blzquez et al., 2000][Eriksson et al., 2006][Blzquez et al., 1997] -- [View TAIR record]

AGL24 -- [Lee et al., 2008][Gregis et al., 2009][Grandi et al., 2012][Tao et al., 2012][Pastore et al., 2011] -- [View TAIR record]

TFL1 -- [Ratcliffe et al., 1999] -- [View TAIR record]

SPL4 -- [Wang et al., 2009][Yamaguchi et al., 2009] -- [View TAIR record]

BAF60, CHC1 -- [Sacharowski et al., 2015] -- [View TAIR record]

FUL, AGL8 -- [Balanz et al., 2014] -- [View TAIR record]

RGL1 -- [Blzquez et al., 2000][Eriksson et al., 2006][Blzquez et al., 1997] -- [View TAIR record]

LFY -- [Winter et al., 2011] -- [View TAIR record]

AP1 -- [Smaczniak et al., 2012][Kaufmann et al., 2010][Wellmer et al., 2006] -- [View TAIR record]

SPL3 -- [Wang et al., 2009][Yamaguchi et al., 2009] -- [View TAIR record]

PNY, RPL, BLR -- [Smaczniak et al., 2012] -- [View TAIR record]

AGL17 -- [Han et al., 2008] -- [View TAIR record]

RGA1 -- [Blzquez et al., 2000][Eriksson et al., 2006][Blzquez et al., 1997] -- [View TAIR record]

RGL3 -- [Blzquez et al., 2000][Eriksson et al., 2006][Blzquez et al., 1997] -- [View TAIR record]

SVP -- [Liu et al., 2009][Gregis et al., 2009][Grandi et al., 2012][Tao et al., 2012][Pastore et al., 2011] -- [View TAIR record]



Protein-protein interactions

SEP3 -- [Liu et al., 2009] -- [View TAIR record]

UFO -- [Parcy et al., 1998][Levin et al., 1995][Chae et al., 2008][Lee et al., 1997] -- [View TAIR record]


LMI2, MYB17 -- [Pastore et al., 2011] -- [View TAIR record]



LFY interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins