Protein function
Encodes a subunit of the delta DNA polymerase II.
Phenotype
Remarks: gis5 mutant is hypomorphic, since null mutant is lethal.
[Iglesias et al., 2015] Remarks: gis5 single mutant has more H3K4me3 activating marks at the
SEP3 locus when grown at higher temperature (24C vs 18C).
[Iglesias et al., 2015] Single mutant: gis5 single mutant is early flowering under both SD and LD conditions. (Under SD conditions, the late-flowering phenotype is stronger at 24C than 18C.)
[Iglesias et al., 2015] Remarks: gis5 single mutant is thermosensistive, has pleiotropic defects, and is unable to complete a full developmental cycle when grown at 28C.
[Iglesias et al., 2015] Function:This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3 - to 5 -direction.
[Data from UniProt]
Regulators, targets and interactors
Downstream actors
Upstream actors
Protein-protein interactions