Detailed gene information

Genes [306]




HTA11
HISTONE H2A 11
TAIR: AT3G54560
UNIPROT: O23628
NOWOMICS: View List

Publications

Anand A et al., 2007, Plant Cell
Choi K et al., 2007, Development
Deal R B et al., 2007, Plant Cell
March-Daz R et al., 2008, Plant J.
Kumar S V et al., 2010, Cell
Coleman-Derr D et al., 2012, PLoS Genet.

Appears in the following schemes

General processes & autonomous pathway

Protein function

Encodes a histone H2A.Z variant protein.

Phenotype

Single mutant:
hta11 single mutant does not display any flowering-time phenotype. [March-Dü¾™†”¼az et al., 2008]

Multiple mutant:
hta8;hta9;hta11 multiple mutant is early flowering under both SD and LD conditions. [Coleman-Derr et al., 2012]

Multiple mutant:
hta9;hta11 multiple mutant is early flowering under both SD and LD conditions. [March-Dü¾™†”¼az et al., 2008]

Remarks:
hta9;hta11 multiple mutant shows reduced FLC expression level. [March-Dü¾™†”¼az et al., 2008]

Artificial microRNA:
Downregulation of both HTA9 and HTA11 by artificial microRNAs leads to an early flowering-time phenotype under LD conditions. ( No data under SD conditions.) [Choi et al., 2007]

Function:
Variant histone H2A which may replace conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). [Data from UniProt]

Regulators, targets and interactors

Downstream actors


Upstream actors


Protein-protein interactions

PIE1 -- [Choi et al., 2007] -- [View TAIR record]

SEF, SWC6 -- [Choi et al., 2007] -- [View TAIR record]



HTA11 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins